Demo

Scientist II

Guardant Health
Palo Alto, CA Full Time
POSTED ON 3/27/2026
AVAILABLE BEFORE 5/26/2026

Company Description

Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn , X (Twitter) and Facebook .

As a Scientist II in the Technology Development Team, you will work collaboratively with team members and interface cross-functionally with bioinformatics, process engineering, system engineering, and other assay development teams. You will be hands-on in the lab to evaluate and optimize new assays related to liquid biopsy sequencing technologies for detecting, treating, and monitoring all cancer types. You will play a critical role in the design and implementation of our advanced cancer diagnostics product as well as future product offerings.

Essential Duties and Responsibilities:

  • Assess, optimize, and implement cutting-edge research and technologies in molecular oncology and diagnostics to improve assay performance

  • Identify areas for improvement in current assays and propose and implement solutions

  • Collaborate within Technology Development and cross-functionally with bioinformatics as well as other cross-functional teams to facilitate effective execution of product goals

  • Be highly committed to deliver results in a fast-paced environment

  • Document technical evaluations and provide SOPs as needed

  • Present data, proposals, and progress in various forums

Qualifications:

  • PhD degree in molecular biology, biomedical sciences, or related field with at least 2-5 years of related experience

  • Experience in research, development and/or optimization of NGS technologies with strong preference for experience with cell-free nucleic acids

  • Knowledge working with automated liquid handlers

  • Strong data analysis skills with experience with Python, R, SQL, or JMP and experience in handling large datasets

  • Familiarity with employing AI tools a plus

  • Detail orientated with demonstrated ability to organize, document and communicate scientific data

  • Committed team player; enjoys working both independently and collaboratively in a fast-paced environment and able to adapt to change.

  • Strong underlying curiosity and drive


Hybrid Work Model: This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate’s compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need. Primary Location: Palo Alto, CA Primary Location Base Pay Range: $122,600 - $168,600 Other US Location(s) Base Pay Range: $104,210 - $143,310 If the role is performed in Colorado, the pay range for this job is: $110,340 - $151,740


Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com

A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.

To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants .

Please visit our career page at: http://www.guardanthealth.com/jobs/

Salary : $104,210 - $143,310

If your compensation planning software is too rigid to deploy winning incentive strategies, it’s time to find an adaptable solution. Compensation Planning
Enhance your organization's compensation strategy with salary data sets that HR and team managers can use to pay your staff right. Surveys & Data Sets

What is the career path for a Scientist II?

Sign up to receive alerts about other jobs on the Scientist II career path by checking the boxes next to the positions that interest you.
Income Estimation: 
$125,958 - $157,570
Income Estimation: 
$120,989 - $162,093
Income Estimation: 
$74,806 - $91,633
Income Estimation: 
$71,928 - $87,026
Income Estimation: 
$145,337 - $174,569
Income Estimation: 
$87,704 - $110,366
Income Estimation: 
$120,989 - $162,093
Income Estimation: 
$74,806 - $91,633
Income Estimation: 
$71,928 - $87,026
Income Estimation: 
$145,337 - $174,569
Employees: Get a Salary Increase
View Core, Job Family, and Industry Job Skills and Competency Data for more than 15,000 Job Titles Skills Library

Job openings at Guardant Health

  • Guardant Health Palo Alto, CA
  • Company Description Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer... more
  • 9 Days Ago

  • Guardant Health Palo Alto, CA
  • Company Description Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer... more
  • 9 Days Ago

  • Guardant Health Brooklyn, NY
  • Company Description Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer... more
  • 10 Days Ago

  • Guardant Health Palo Alto, CA
  • Company Description Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer... more
  • 10 Days Ago


Not the job you're looking for? Here are some other Scientist II jobs in the Palo Alto, CA area that may be a better fit.

  • Joulé Pleasanton, CA
  • Job Title: Scientist II Location: Pleasanton, CA Type: Contract Compensation: $45.00 - $55.00 hourly Job Description : Join a dedicated team of scientists ... more
  • 2 Months Ago

  • 10x Genomics Pleasanton, CA
  • About The Role 10x Genomics is establishing a diagnostics effort, translating our leading single-cell and spatial assay technologies into impactful clinica... more
  • 10 Days Ago

AI Assistant is available now!

Feel free to start your new journey!