Demo

Director Clinical Development Operations

GQR
San Diego, CA Full Time
POSTED ON 4/17/2026
AVAILABLE BEFORE 5/16/2026

Sr/Director, Clinical Development Operations

San Diego, CA | Hybrid / Remote with Travel


A next‑generation RNA therapeutics company in San Diego is exploring interest in a future Director/Senior Director of Clinical Development Operations to lead early‑phase clinical execution for breakthrough cardiovascular programs. This role blends strategic leadership with hands‑on operational ownership in a fast‑moving, high‑innovation environment.


Responsibilities

• Lead strategic planning and execution of early‑phase clinical trials, including first‑in‑human studies

• Build, scale, and shape the clinical operations function from the ground up

• Partner closely with Clinical Development on study design, protocol development, and operational strategy

• Lead cross‑functional planning, timelines, budgets, and risk management

• Manage CROs, vendors, and internal clinical teams to ensure high‑quality, inspection‑ready delivery

• Drive patient‑centric trial design and recruitment strategies

• Guide site feasibility, study start‑up, and global execution

• Manage timelines, budgets, risks, and cross‑functional communication

• Establish and refine processes, tools, and systems to elevate operational excellence

• Partner closely with Clinical Development, Regulatory, CMC, and Preclinical teams

• Support regulatory interactions, data review, and program‑level decision making


Requirements

• BS, advanced degree preferred (PhD/MD)

• 10 years in clinical development/clinical operations within biotech or pharma

• Strong background in cardiology clinical research

• Experience with RNA therapeutics strongly preferred

• Proven leadership in global clinical development execution

• Strategic thinker who’s also comfortable rolling up their sleeves

• Creative, solution‑oriented, and energized by building in ambiguity

• Excellent communication, project management, and stakeholder leadership

Salary.com Estimation for Director Clinical Development Operations in San Diego, CA
$130,577 to $163,007
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