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Postdoctoral Scientist, Structural Biology

Gilead.com
California, CA Full Time
POSTED ON 11/17/2025
AVAILABLE BEFORE 12/16/2025
Job Description

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Job Description

The Structural Biology Group at Gilead Sciences is seeking a highly motivated postdoctoral scientist to join our team in Foster City. The Structural Biology Group has a modern X-ray crystallography lab with high throughput crystallization robotics and frequent access to major synchrotrons, and hosts a recently established state-of-the-art cryo-EM facility with in-house Glacios and Krios G4 microscopes supported by high performance and high capacity computational infrastructure. The Structural Biology group collaborates closely with other functions such as Computational Modeling, Research Informatics, Medicinal Chemistry and Protein Therapeutics, to provide timely and enabling structural information to support diverse research projects spanning therapeutic areas such as virology, oncology, and inflammation.

This postdoc scientist will be utilizing protein biochemistry, biophysics, and structural biology techniques to elucidate the molecular mechanism of important drug targets including both small molecule and biologics programs. As part of the training, the candidate will also contribute to new cryo-EM methods development and implementation.

The successful candidate is expected to have a solid training in single particle cryo-EM and strong scientific experience as evidenced by first-author publications in top-tier scientific journals. The candidate should demonstrate excellent presentation (written & oral), collaboration and interpersonal skills.

Responsibilities:

  • Construct design, protein expression and purification for structural studies.
  • Cryo-EM sample preparation & optimization, data collection and structure determination of target complexes.

Basic Qualifications:

  • Ph.D in structural biology, biochemistry, or a related field.

Preferred Qualifications:

  • Experience in laboratory techniques supporting structural biology and recombinant protein purification, membrane protein experience is highly desirable.
  • Strong communication and interpersonal skills, and the ability to work flexibly in a dynamic and collaborative environment.
  • Demonstrated a strong track record of independent critical thinking and scientific achievement in research, exemplified by publications in highly regarded journals, conference presentations or generation of intellectual property.

The salary range for this position is: $126,820.00 - $164,120.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may be eligible for paid time off and a benefits package. Benefits MAY include company-sponsored medical, dental, vision, and life insurance plans*. This position is not eligible for a discretionary annual bonus or discretionary stock-based long-term incentives.

For Additional Benefits Information, Visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

  • Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

For Jobs In The United States:

Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance.

For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.

NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT

YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT

PAY TRANSPARENCY NONDISCRIMINATION PROVISION

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees And Contractors:

Please apply via the Internal Career Opportunities portal in Workday.

Salary : $126,820 - $164,120

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