Demo

Purification Development Scientist

Genentech and Careers
Philadelphia, PA Full Time
POSTED ON 12/26/2025
AVAILABLE BEFORE 2/25/2026
THE POSITION


The Opportunity


The downstream process development (DSPD) team is seeking a highly motivated associate scientist/scientist with relevant industry experience to join the team. The successful candidate will participate in multiple downstream process development programs in Roche’s innovative pipeline.

What You’ll Do


  • Execute lab experiments according to predefined experimental design and protocols.

  • Support the maintenance of essential equipment and critical raw materials to ensure smooth laboratory operations.

  • Maintain comprehensive and accurate documentation with a high level of detail. Close out experiments in a timely manner while preparing and submitting well-written development reports.

  • Collaborate with team members to ensure the DSP laboratories are maintained in a professional and organized working environment.

  • Contribute to the troubleshooting, optimization, and scale-up of downstream processes to meet project objectives.

Skill & Mindset

  • Strong organizational skills and detailed documentation abilities are required.

  • Perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies.

  • Excellent writing and verbal communication skills are required.

  • Teamwork is a must.

  • Must be comfortable in the fast-paced, multi-tasking biotech environment

  • Perform experiments with moderate complexity.

  • Detail oriented data recording and analysis.

  • Be able to identify issue and problems proactively, suggest solutions and solicit group members' inputs and feedbacks


The PD Downstream Scientist will work with members of PD downstream, upstream, analytical development, MS&T, PCO groups. If necessary, the PD Downstream scientist also needs to contact vendors and consultants, to bring in and evaluate new equipment and materials.

Who You Are

PhD in biochemistry, chemistry, chemical engineering, bioengineering, or related area with 0-3 years of relevant industry experience.

Master's/Bachelor's in biochemistry, chemistry, chemical engineering, bioengineering, or related area with 3-7 years of relevant industry experience.

  • Knowledge of downstream process development of the biologics, such as viral vectors, monoclonal antibodies, vaccines, and therapeutic recombinant proteins in the biopharma industry

  • Hands-on experience with operating chromatography and filtration systems

  • Working knowledge and skills for viral vector or vaccine purification is a plus.

  • Working knowledge of analytical techniques for in process testing or product characterization is a plus

  • In-depth understanding in at least one of the following aspects is a plus: Chromatography, Tangential Flow Filtration (TFF) operations or pilot-scale operations.


Other Job Requirements


  • Must be able to lift 25 pounds

  • Must be flexible with work schedule and available to work extended hours if needed

  • Must be able to wear all Personal Protective Equipment as required

  • Must be able to stand for long periods

Relocation funding is not available for this role.

The expected salary range for this position based on the primary location of Philadelphia, Pennsylvania is $91,000 - $169,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

JOB FACTS
    Job Sub Category

    Process Development

    Schedule

    Full time

    Job Type

    Regular

    Posted Date

    Dec 18th 2025

    Job ID

    202512-132256

Salary : $91,000 - $169,000

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