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Research Associate II, Single Cell and Spatial Core

Frederick National Laboratory for Cancer Research
Bethesda, MD Full Time
POSTED ON 11/5/2026
AVAILABLE BEFORE 12/4/2026
Job ID: req4736

Employee Type: exempt full-time

Division: Cancer Research Technology Program

Facility: NIH

Location: NIH Campus 9000 Rockville Pike, Bethesda, MD 20892 USA

The Frederick National Laboratory is operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.

Program Description

The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI's intramural Center for Cancer Research (CCR). The dedicated units provide expertise in electron microscopy, protein characterization, mass spectrometry, protein expression, optical microscopy, and genomics. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research (FNLCR), where CRTP scientists work collaboratively with intramural NCI investigators to provide research technologies and expertise.

Key Roles/Responsibilities

We are seeking a highly motivated Research Associate to join the Single Cell and Spatial Core (SCSC) of the Center for Cancer Research (CCR) at NCI. The SCSC provides support for state-of-the-art single cell sequencing and spatial profiling technologies to basic and translational cancer research.

This Research Associate Will Have a Role In

  • Supporting single cell sequencing projects, including performing cell counts, generating next generation sequencing libraries, performing sequencing, and assessing resulting data in coordination with other members of the SCSC team.
  • Assisting with general upkeep of the lab, including archiving samples, ordering, and managing stock levels.
  • Collaborating with other members of the SCSC team to support experimental design, sample preparation, and project troubleshooting.

Additional tasks may be assigned, and work responsibilities may change as the Single Cell and Spatial Core evolves to support the needs of NCI CCR.

This is a laboratory-based position that is onsite on the main NIH Bethesda campus. There may be occasions when you will be expected to work beyond the standard 8-hour day or adjust your work schedule to accommodate the handling of samples later in the day.

Basic Qualifications

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

  • Possession of Bachelor’s degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years relevant experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency.
  • In addition to the education requirement, a minimum of five (5) years of experience performing cell and molecular biology experiments.
  • Familiarity with next generation sequencing methods.
  • Ability to obtain and maintain a security clearance.

Preferred Qualifications

Candidates with these desired skills will be given preferential consideration:

  • Demonstrated experience in the area of single cell assays and sequencing.
  • Experience with next generation sequencing (NGS) library preparation, and DNA quantitation.
  • General knowledge and experience with cell biology, including cell culture, cell sorting, viability assessment, and counting.
  • Experience working in a core facility or other team-based environment.
  • Demonstrated ability to rapidly learn new technologies and troubleshoot experiments and assay workflows.
  • Knowledge and background experience in cancer biology and immunology.
  • Excellent written and verbal communication skills.
  • Strong attention to detail and organizational skills, with the ability to manage multiple projects concurrently while maintaining high-quality work.

JOB HAZARDS

  • This position is subject to working with or has the potential for exposure to animals(s) and/or animal material(s).
  • This position is subject to working with or has the potential for exposure to infectious material, requiring medical clearance and immunizations.

Commitment to Non-Discrimination

All qualified applicants will receive consideration for employment without regard to sex, race, ethnicity, color, age, national origin, citizenship, religion, physical or mental disability, medical condition, genetic information, pregnancy, family structure, marital status, ancestry, domestic partner status, sexual orientation, gender identity or expression, veteran or military status, or any other basis prohibited by law. Leidos will also consider for employment qualified applicants with criminal histories consistent with relevant laws.

Pay And Benefits

Pay and benefits are fundamental to any career decision. That's why we craft compensation packages that reflect the importance of the work we do for our customers. Employment benefits include competitive compensation, Health and Wellness programs, Income Protection, Paid Leave and Retirement. More details are available here

72,200.00 - 103,400.00 USD

The posted pay range for this job is a general guideline and not a guarantee of compensation or salary. Additional factors considered in extending an offer include, but are not limited to, responsibilities of the job, education, experience, knowledge, skills, and abilities as well as internal equity, and alignment with market data.

The salary range posted is a full-time equivalent salary and will vary depending on scheduled hours for part time positions

Salary.com Estimation for Research Associate II, Single Cell and Spatial Core in Bethesda, MD
$134,362 to $164,363
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