What are the responsibilities and job description for the Scientist (non-PhD)- ADC Biology position at Fortira Inc.?
Job Title: Scientist (non-PhD)- ADC Biology
Location: Bothell, WA
Workplace Type: Onsite
Work Schedule: Mon to Fri
Job Type : Contract, 6 months
No of roles : 1
ROLE SUMMARY
As a Scientist (non-PhD) on our ADC Biology team, you will be a key driver in advancing next-generation ADC technologies through collaborative, cross-functional research that spans from early discovery to pre-clinical development. You will develop assays and execute screening and identification of novel chemotypes that function as payloads for antibody drug conjugates for cancer therapy. You will work collaboratively with chemistry and other cross functional teams to understand mechanism of action of identified payloads. You will analyze, interpret and communicate the data effectively to key stake holders.
KEY RESPONSIBILITIES
- Apply cellular, biochemical, immunological, and molecular biology laboratory techniques to preclinical research projects in the areas of Cancer signaling and Cancer biology
- Investigate MOAs of our therapeutics through development, optimization, and execution of complex assays
- Interact and collaborate with other functional groups across research
- Provide leadership within technical area of expertise; may train, direct or mentor others
- Design and execute key experiments to investigate novel therapeutic targets and MOAs of novel payloads to enable clear go/no-go decisions.
- Independently analyze data, document results, and present findings to large and small audiences
- Maintain rigorous records of experimental progress using electronic laboratory notebooks
- Present experimental results and scientific rationale to colleagues
- Execute molecular, biochemcial and cell-based methodologies including cytotoxicity assays, HiBit, HTRF, ELISA, western blotting, automated liquid handling multicolor flow cytometry, immunofluorescence and live cell microscopy.
- Aid in execution and analysis of additional experiments as need arises within the ADC discovery research team
MINIMUM REQUIREMENTS
- Bachelor's degree in Cellular or Molecular Biology, Immunology, Biochemistry or related field and 6 years' relevant industry experience OR M.S. degree in Cellular or Molecular Biology, Immunology, Biochemistry or related field with 4 years' relevant industry experience
- Experience with Microsoft Office (Excel, Word, PowerPoint) and analytical (Prism, FlowJo, etc.) software programs
- Experience designing, performing and interpreting complex experiments that require significant insight into problems being addressed with some guidance
- Working knowledge in specific areas of Cancer Biology and Cancer therapeutics esp, small molecule agents, Biologics and ADCs
- Experience working independently and working on multiple projects
- Experience collaborating across teams and a variety of disciplines to provide experimental expertise and support others on joint projects
- Experience leading parts of projects or initiatives within area of expertise
- Excellent written/oral communication skills with experience presenting/sharing details of the work with key stake holders
PREFERRED REQUIREMENTS
- Experience in experimental cancer biology, biochemical and/or immunological techniques (e.g., Cell culture, cytotoxicity assays, HiBit, HTRF, ELISA, western blotting, automated liquid handling multicolor flow cytometry, immunofluorescent and live cell microscopy.).
- Background knowledge of the field of cell signaling and biochemistry
- Experience developing complex cell and biochemical assays