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Senior Manager / Associate Director, Product and Pipeline Operations

Flagship Pioneering
Cambridge, MA Full Time
POSTED ON 12/10/2025 CLOSED ON 1/6/2026

What are the responsibilities and job description for the Senior Manager / Associate Director, Product and Pipeline Operations position at Flagship Pioneering?

Position Summary:

The Associate Director, P&PI Operations, will play a central role in supporting the operations and governance of P&PI and the Product and Partnering Review Committee (PPRC). Reporting to the Director, P&PI Operations, this individual will ensure seamless coordination, documentation, and process improvement across portfolio governance activities. The role requires a detail-oriented, proactive, and highly organized professional who can manage complex cross-functional processes and drive accountability across teams.

Flagship is an experiment in institutional, entrepreneurial innovation practiced in the context of a small company with an insurgent mindset. We are seeking individuals with an entrepreneurial spirit, strong communication skills, and comfort working in and contributing to a dynamic and cross-functional team environment. The level of the role will be commensurate with the education and years of experience of the identified candidate.

Key Responsibilities:

  • Engages in a process with leadership of prioritizing the most compelling concepts that could become ProtoCos, Flagship’s first stage of development
  • Build strong relationship across Flagship and the dozens of Flagship platform companies as part of understanding the capabilities of each platform, present and planned.
  • Balances unconstrained, highly creative thinking with an Exploration Method that has been designed to create product concepts with transformational clinical outcomes at the end of an Exploration process that runs several months
  • Establishes a close partnering relationship with each team member. Contributes to a high-energy team spirit and high functioning team and leads in a way that is consistent with Pioneering Medicines’ values

Minimum Qualifications:

  • 8 years of experience in operations, portfolio management, or program governance within biotechnology, pharmaceuticals, or a related R&D environment.
  • Proven ability to manage complex calendars, governance workflows, and cross-functional communications.
  • Exceptional organizational and prioritization skills with keen attention to detail.
  • Strong written and verbal communication skills; able to synthesize discussions into actionable summaries.
  • Proficiency with collaboration and tracking tools (e.g., SharePoint, Smartsheet, Notion, Microsoft Office, AI-based productivity tools).
  • Demonstrated ability to partner across scientific, operational, and leadership teams in a fast-paced, evolving environment.
  • Proven ability to build and sustain strong working relationships across diverse stakeholder groups, fostering collaboration, trust, and alignment.
  • High degree of professionalism, discretion, and accountability.

Values and Behaviors

  • Entrepreneurial spirit and mission-oriented toward enabling breakthrough innovation.
  • Courage to take initiative and drive improvements across teams and processes.
  • Collaborative mindset with strong interpersonal and communication skills.
  • Commitment to fostering a growth-oriented, high-energy environment.
  • Accountability for high-quality execution and follow-through.

WHAT WE OFFER:

  • Impactful role in a company recognized for transformative contributions to human health and sustainability.
  • Dynamic culture with inspiring colleagues and leaders.
  • Support for professional development and growth in an innovative environment.
    • Comprehensive employee benefits and rewards program.
LOCATION: Cambridge, MA

ABOUT FLAGSHIP PIONEERING

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $128,000 - $203,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

Salary : $128,000 - $203,000

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