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Senior Engineer II, Mechanical/Dispersion Systems

Flagship Pioneering
Flagship Pioneering Salary
Boulder, CO Full Time
POSTED ON 5/5/2026
AVAILABLE BEFORE 10/31/2026
COMPANY DESCRIPTION

Flagship Pioneering is a bioplatform innovation company that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health, sustainability and beyond exponentially accelerate scientific progress in areas ranging from disease detection and treatment and nature-positive agriculture to novel applications of AI that are driving the creation of new technologies.

What sets Flagship apart is our ability to advance science and technology by uniting innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies.

THE ROLE

We are seeking a highly motivated, proactive, and detail-oriented Sr. Engineer II, Mechanical/Dispersion Systems to lead the design and development of aerosol dispersal systems. This role will be responsible for owning the mechanical design and performance of systems that control the release and distribution of particulate materials in real-world trials.

The ideal candidate combines strong fundamentals in fluid/particle dynamics with hands-on experience building and iterating physical systems. The individual will work cross-functionally with scientists, engineers, and external partners to translate novel materials into robust hardware. Success in this role requires comfort operating in a fast-paced, experimental environment and the ability to independently drive complex engineering efforts from concept through deployment.

KEY RESPONSIBILITIES

  • Lead the design and development of dispersion systems, owning mechanical performance from concept through prototyping and validation.
  • Design and optimize particle and fluid handling systems, including mechanisms for controlled release, flow regulation, and dispersal behavior.
  • Develop hardware intended for integration with mobile and diverse platforms, accounting for size, weight, power, and environmental constraints.
  • Rapidly prototype and iterate on designs using hands-on build methods (e.g. 3D printing, machining) with a strong emphasis on learning and designing through experimentation.
  • Design and execute bench-scale tests to evaluate system performance, including flow rates, particle distribution, and repeatability.
  • Work with external manufacturers and machine shops to fabricate components, refine designs for manufacturability, and scale builds.

PROFESSIONAL EXPERIENCE & QUALIFICATIONS

  • Bachelor’s degree in mechanical, aerospace or related engineering discipline with 8 years of relevant industry experience, or Master’s degree with 6 years of experience, or PhD with 3 years of experience.
  • Strong foundation in fluid dynamics and particle behavior with experience designing systems involving spray or particulate dispersion.
  • Demonstrated ability to own end-to-end mechanical design from concept -> prototype -> testing -> iteration.
  • Proficiency in 3D CAD tools (SolidWorks, Fusion, OnShape).
  • Must be available for onsite employment in North Denver/Boulder Metro, Colorado.
  • Initiative and ability to manage multiple, competing priorities, to think strategically and execute methodically.
  • Strong organizational and project management skills, with the ability to independently drive initiatives in a fast-paced environment.
  • Excellent communication and documentation skills, with the ability to clearly articulate design decisions and tradeoffs.

LOCATION: Boulder, CO

ABOUT FLAGSHIP PIONEERING:

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.

Salary.com Estimation for Senior Engineer II, Mechanical/Dispersion Systems in Boulder, CO
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