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Scientist, Computational Biology

Flagship Pioneering
Flagship Pioneering Salary
Cambridge, MA Full Time
POSTED ON 9/25/2025
AVAILABLE BEFORE 11/10/2025
What if you could join a rapidly growing company and play a critical role in bringing new medicines to patients through looking at and treating disease in a revolutionary way?

About Vesalius

Vesalius Therapeutics is pioneering a revolutionary platform to generate breakthrough treatments for common diseases. Vesalius’ platform uses large-scale human genetics, genomics, stem cell studies and artificial intelligence to uncover causal biology and identify optimal intervention points for new therapies. Efficiently identifying these intervention points and the patients most likely to benefit from these novel therapies will enable smaller, shorter clinical trials with a higher probability of success. Vesalius was founded in 2019 by Flagship Pioneering. For more information visit vesaliustx.com, or follow us on X and LinkedIn.

The Role

Vesalius Therapeutics is seeking a computational biologist with experience in Bayesian inference, network analysis (structure learning, counterfactual inference), and/or sequence modeling (sgRNA design, mutation/selection, prediction) to join our team. You will report to the Head of Data Science and apply or develop state-of-the-art computational methods to deliver biological insights combining internally generated and external data sets. You will bring a solid foundation in applied statistics, high-performance, scalable, reproducible scientific code (demonstrated by a public Github repository), and molecular, cell, or tissue biology. You will work both independently and in matrixed teams with wet lab scientists, statistical geneticists, and machine learning scientists to redefine common diseases and develop new therapeutics to address unmet need.

What You’ll Do:

  • Deliver biological insights into cellular networks, patient biomarkers, and/or in-vitro physiological models and champion decisions and next steps
  • Identify relevant external data sets and new opportunities/needs for internal data generation
  • Write and deploy high-performance code/pipelines for large-scale computation
  • Communicate to both technical and non-technical audiences clearly in writing and speaking

What You’ll Bring:

  • PhD. in Computer Science, Computational Biology, Biostatistics, Physics, Mathematics, Statistics, or related field
  • Additional experience desirable but not required
  • Demonstrated proficiency in a relevant programming language (Python, R, etc.) supported by a public Github repository
  • Experience developing novel models, algorithms, or software implementations a plus
  • Strong communication skills in writing and speaking

About Flagship

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Vesalius is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

At Vesalius, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Vesalius Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Vesalius or its employees is strictly prohibited unless contacted directly by the Vesalius internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Vesalius, and Vesalius will not owe any referral or other fees with respect thereto.

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