Senior Business Systems Analyst

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At Exact Sciences, we’re helping change how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you’re working to help others.

Position Overview

The Sr. Laboratory Business Systems Analyst serves as a strategic liaison among business stakeholders, IT Application Analysts, and Operations Analytics—translating complex business needs into robust Laboratory

Business System solutions that improve operational performance. The senior analyst independently leads medium-sized initiatives (and critical workstreams within larger programs), mentors junior analysts, and

ensures systems and processes remain aligned to business goals and the Quality Management System. This role demands strong analytical skills, clear cross-functional communication and a track record of successful

project delivery in a fast-paced environment

Essential Duties

Include but are not limited to the following:

• Independently lead complex initiatives with broad scope and minimal oversight.
• Independently gather and document requirements, translate them into designs aligned to established standards, and propose design improvements for review and approval.
• Lead project steps and contribute to analysis, design, testing, deployment, and cross-functional issue resolution.
• Lead and execute end-to-end functional testing and UAT cycles, ensure testing completeness and quality, contribute to SOP user documentation, and lead post–go-live stabilization efforts.
• Serve as an advanced support resource by troubleshooting complex issues, performing root cause analysis, and recommending durable corrective actions. Share triage and escalation guidance with peers.
• Communicate clearly with internal stakeholders, leaders, and external vendors, translating technical concepts for non-technical audiences.
• Lead change management initiatives including development and ownership of SOPs and advanced training materials. Deliver targeted end-user training to drive adoption and sustainment.
• Help develop roadmap for supported system(s) and processes
• Continuously learn and apply new related skills and capabilities
• Maintain regular and reliable attendance.
• Act with an inclusion mindset and model these behaviors for the organization.
• Ability to lift up to 10 pounds for approximately 5% of a typical working day.
• Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 80% of a typical working day.
• Ability to travel 5% of working time away from work location. May include overnight/weekend travel.
  
  

Minimum Qualifications

• Bachelor’s Degree in a field related to essential duties; or Associates Degree and 2 years of relevant experience; or High School Diploma or General Education Degree (GED) and 4 years of relevant experience.
• 5 years of experience as a business analyst designing and supporting processes in related systems
• Experience leading system enhancement or implementation projects.
• Proficient in Microsoft Office.
• Applicants must be currently authorized to work in country where work will be performed on a full or part-time basis. We are unable to sponsor or take over sponsorship of employment visas at this time.
• Demonstrated ability to perform the Essential Duties of the position with or without accommodation.
  
  

Preferred Qualifications

• Bachelor’s degree in Operations, Supply Chain, Computer Science or Management Information Systems.
• Proficiency in Atlassian (Confluence, Jira and Zephyr) or other digital project management platforms
• Experience supporting business processes in advanced digital laboratory systems solutions (LIS/LIMS).
• Experience with AI platforms for developing practical agentic solutions
• Experience in a biotech/life sciences manufacturing environment; preferably in a cGMP, GLP, ISO 13485, and/or CLIA environment.
• Experience at a company with Computer Systems Validation processes in place or equivalent best practices and of change control as it relates to application systems.
• Lean Six Sigma Green Belt certification.
• Experience with SAP Fiori apps as a business user or in an analyst role
  
  

Salary Range:

$91,000.00 - $155,000.00

The annual base salary shown is for this position located in US - WI - Madison on a full-time basis. In addition, this position is bonus eligible.

Exact Sciences is proud to offer an employee experience that includes paid time off (including days for vacation, holidays, volunteering, and personal time), paid leave for parents and caregivers, a retirement savings plan, wellness support, and health benefits including medical, prescription drug, dental, and vision coverage. Learn more about our benefits.

Our success relies on the experiences and perspectives of a diverse team, and Exact Sciences fosters a culture where all employees can develop personally and professionally with a sense of respect and belonging. If you require an accommodation, please contact us here.

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We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to disability, protected veteran status, and any other status protected by applicable local, state, or federal law.

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