Senior Associate Scientist, Protein Science

Company Description Evive Biotech, a subsidiary of Yifan Pharmaceutical, is a global biologics company developing a portfolio of novel biologic therapies for patients worldwide. Leveraging our proprietary technology platforms, we are advancing a pipeline of innovative drug candidates targeting oncology and inflammation.

Founded in 2004, Evive has grown to approximately 300 employees with operations in the United States, Singapore, and China.

We are seeking a highly motivated Senior Associate Scientist, Protein Science, to join our R&D team in Hayward, California. This position offers an exciting opportunity to contribute to the discovery of next-generation therapeutics while working in a collaborative, fast-paced, and scientifically driven environment.

Responsibilities

• Recombinant protein expressions in mammalian cell lines.
• Perform protein purification, characterization for quality, and document work in electronic lab notebook.
• Troubleshoot cloning, protein expression and purification workflows.
• Maintain the protein and plasmid inventories.
• Analyze experimental data critically, draw scientific conclusions, and effectively communicate findings to cross-functional project teams.
• Maintain accurate and timely documentation of experimental procedures, data, and analyses in electronic laboratory notebooks (ELNs).
• Collaborate effectively with colleagues across global research sites.

Qualifications Required

• PhD in biochemistry, biophysics or other relevant fields, or MS/BS in biochemistry, biophysics or other relevant fields with more than 5 years’ research experience.
• Hands-on experience in protein purification techniques including affinity, ion exchange, size exclusion, hydrophobic interaction chromatography using AKTA Avant/Pure
• Proficiency with various analytical protein characterization techniques such as SEC-HPLC, HIC-HPLC and SDS-PAGE.
• Excellent organizational skills with meticulous attention to detail and accurate documentation practices.
• Strong written and verbal communication skills and the ability to work collaboratively within multidisciplinary teams.
• Self-motivated, resourceful, adaptable, and able to prioritize effectively in a fast-paced, timeline-driven research environment.
• Willingness to tackle challenging technical problems.

Preferred

• Experience in antibody discovery pipelines: expression, purification, screening, and analytical characterization. Experience in oncology and/or immunology drug discovery.
• Experience in protein engineering along with biophysical characterization methods for protein-protein interactions, such as surface-plasmon resonance (SPR) or bio-layer interferometry (BLI), will be considered a plus.
• Experience in structural biology is a plus but not required, including protein X-ray crystallography. Familiarity with software such as CCP4, Coot, and PyMOL.
• Experience with molecular cloning techniques, including Gibson Assembly, Golden Gate Assembly, PCR, and site-directed mutagenesis.
• Operating experience with various automation instruments e.g., autosamplers, automated liquid handling systems (EpMotion and Opentrons).

Benefits

• Competitive base salary with annual performance bonus opportunity.
• Comprehensive medical, dental, and vision insurance.
• Life insurance and disability coverage.
• 401(k) retirement plan.
• Generous paid time off and company holidays.
• Opportunities for career advancement and professional development.
• Full-time, on-site position based in Hayward, California.

Equal Opportunity Employer

Evive Biotech is an Equal Opportunity Employer committed to fostering a diverse and inclusive workplace. We make all employment decisions based on business needs, job requirements, and individual qualifications, without regard to race, color, religion, creed, national origin, ancestry, sex, gender identity or expression, sexual orientation, age, disability, veteran status, or any other characteristic protected by applicable federal, state, or local law.