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Senior Manager, Supply Operations

Esperion
Ann Arbor, MI Full Time
POSTED ON 12/3/2025 CLOSED ON 1/3/2026

What are the responsibilities and job description for the Senior Manager, Supply Operations position at Esperion?

Company Overview

Our Mission: At Esperion, we are working tirelessly to deliver innovative medicines that help patients reach their goals today, tomorrow, and into the future.

Esperion is a fully remote based company with a corporate headquarters located in Ann Arbor, MI. The Company offers a competitive salary including a performance-based bonus program and stock-based compensation, a comprehensive benefits package including a 401(k) matching plan and health insurance, and paid time off and holidays.

Position Title: Senior Manager, Supply Operations

The Senior Manager, Supply Operations role is responsible for leading the development and execution of data-driven supply chain strategies that support operational excellence, demand planning, inventory management, and end-to-end supply chain optimization. The incumbent will use data from various sources (including the ERP system) to enable supply chain process improvement and KPI reporting, including facilitation of the monthly S&OP process. This is a high-impact, highly visible role that collaborates closely with cross-functional internal and external teams including Drug Substance and Drug Product Manufacturing, Packaging, Quality, and Finance.

Preferred Location: Remote – US

Essential Duties and Responsibilities*

Strategic Planning & Analysis

  • Using ERP system and other data sources, develop and lead analytical models and dashboards to support supply chain decision-making.
  • Partner with senior leadership to define and execute long-term supply chain strategies.
  • Translate ERP data into actionable insights to improve service levels, reduce costs, and optimize inventory.
  • Collaborate with digital transformation teams to develop and implement ERP system capabilities related to supply chain analytics.
  • Optimize ERP Master Data to enhance supply network visibility.

End-to-End Supply Chain Optimization

  • Identify and lead initiatives to enhance supply chain performance, including network design, supplier performance, and logistics.
  • Develop and implement scenario planning tools to evaluate financial and supply risk and demonstrate supply chain resilience.

Forecasting, Demand Planning, Capacity Planning

  • Analyze domestic forecast accuracy and variability, work with finance and commercial teams to improve forecasting through S&OP process
  • Analyze Partner forecasts to confirm capacity requirements in mid- and long-term horizons
  • Creation and ownership of 5-year capacity model

Operational Reporting & KPIs

  • Develop and maintain dashboards and KPIs to monitor key supply chain metrics such as OTIF, inventory turns, lead times, and service levels.
  • Publish monthly and quarterly KPI and analytics packages internal and external stakeholders.

DSCSA Compliance and Artwork management

  • Ensure all requirements of DSCSA are adhered to, including management of serialization, traceability, partner verification
  • Collaborate with partners and internal teams (QA, Trade & Distribution) to ensure accurate data exchange, and management of suspect or illegitimate products
  • Partner with internal Regulatory and external artwork vendors to ensure timely, accurate implementation of domestic and global Partner artwork changes, including strategic depletion of

Cross-functional Collaboration

  • Serve as a strategic partner to Drug Substance and Drug Product Manufacturing, Quality, and Regulatory teams.
  • Facilitate workshops and working sessions to gather requirements and promote Tech Ops wide continuous improvement initiatives.
  • additional duties and responsibilities as assigned

Qualifications (Education & Experience)

  • Minimum of 5-7 years increasing responsibility in Supply Chain and Manufacturing, focused on the pharmaceutical industry with B.S. in Business from accredited college or university and/or equivalent education and experience. CSCP or CPIM certifications and MBA are highly preferred.
  • Demonstrated MRP/ERP skills, including at least one implementation of SAP, Oracle, etc., systems.
  • Demonstrated ability to work and lead in a dynamic group that takes a multi-disciplined team approach to executing and achieving departmental and corporate goals.
  • Excellent verbal and written communication and presentation skills with high attention to detail.
  • Demonstrated experience in managing pharmaceutical products, which are virtually manufactured globally.
  • Demonstrated ability to successfully work with and influence internal and external (contract manufacturing) partners while maintaining a positive working relationship.
  • Demonstrated strong working knowledge of planning. Competence in material management and forecast planning is required.
  • Strong ability to analyze complex issues to develop relevant and realistic plans, programs, and recommendations.
  • Possess strong conflict management and negotiation skills.
  • Demonstrated experience in the implementation or improvements of supply chains and quality systems in a commercial setting. Strong understanding and working knowledge of cGMPs for pharmaceutical development and commercial operations.
  • Domestic & International travel may be required (10%)

Salary : $165,000 - $185,000

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