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Sr. Manager - Reliability Engineering - Lilly Medicine Foundry

Eli Lilly and Company
Lebanon, IN Full Time
POSTED ON 10/6/2025
AVAILABLE BEFORE 12/5/2025

Job Details

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Organization and Position Overview

Lilly recently announced a $4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The first-ever facility of its kind, combining research and manufacturing in a single location, the Medicine Foundry will allow Lilly to further develop innovative solutions to optimize manufacturing processes and increase capacity for clinical trial medicines, while also reducing costs and environmental impact.

The Senior Manager - Reliability leads the reliability engineering function within the center for advanced manufacturing research, overseeing a team dedicated to maximizing the performance, dependability, and availability of process and utility equipment supporting pharmaceutical research and manufacturing. This leadership role ensures that all reliability programs and initiatives align with the organization's goals for safety, quality, innovation, and operational excellence, directly impacting the delivery of novel medicines for clinical trials.

Responsibilities

In line with the job outlined above, the following are typically the key tasks that would be expected of the role:
  • Direct the strategic development and implementation of reliability programs to support advanced manufacturing research and ensure the highest standards of equipment performance, safety, and compliance.
  • Overall ownership and responsibility for system and equipment reliability programs for all Lilly Medicine Foundry (LMF) assets.
  • Lead, mentor, and develop a team of reliability engineers and technicians, fostering a culture of continuous improvement, collaboration, and technical excellence.
  • Ensure robust monitoring, reporting, and analysis of equipment performance data to proactively identify trends, implement corrective actions, and prevent potential reliability issues.
  • Support cross-functional teams within manufacturing and research by ensuring all equipment and utilities enable uninterrupted, high-quality, and compliant pharmaceutical development.
  • Champion health, safety, environmental, and cost optimization objectives as part of overall reliability strategy.
  • Engage with external partners, conferences, and training opportunities to keep the organization at the forefront of reliability engineering advancements.
  • Ensure performance and corrective action of root cause failure analysis on systems and components.
  • Perform all supervisory tasks including performance management activities for reliability engineers and technicians.
  • Ensure oversight of the mechanical integrity program for LMF.
  • Align the local reliability program with Lilly's global reliability program through the Engineering Technology Center (ETC), while also allowing flexibility and adaptability of the Foundry's critical assets.
  • Leverage new technologies such as Artificial Intelligence (AI) in order to drive innovation in the reliability arena by identifying data trends and enabling predictive / proactive maintenance best practices.

Basic Requirements:
  • Bachelor of Science in Engineering or a related technical field
  • Professional experience in reliability engineering or a related field, proven leadership and people management skills.
  • Demonstrated expertise in equipment reliability programs, predictive maintenance, and advanced analytical methods.
  • Strong organizational, communication, and stakeholder engagement abilities.

Additional Preferences:
  • Certified Reliability Engineer or Certified Maintenance & Reliability Professional
  • Strong knowledge of Maximo/GMARS and Business Objects
  • Strong knowledge of FDA GMPs, ISO standards, deviation management and change controls
  • Knowledge of automation systems/software to facilitate data collection (e.g., data historians)
  • Training in RCM, FMEA, and/or RCFA facilitation
  • Six Sigma Green Belt
  • Knowledge of Weibull analysis, Life Cycle Cost analysis, TPM practices

Other Information:
  • Initial location at Lilly Technology Center, Indianapolis.
  • Permanent location at the new Lilly Medicines Foundry in Lebanon, Indiana.
  • Must be available to provide leadership and guidance outside of standard working hours when necessary, including on-site presence for critical incidents.
  • Willingness to travel offsite to support the business, attend external conferences, or participate in specialized training as required.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$99,000 - $145,200

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly
Employers have access to artificial intelligence language tools (“AI”) that help generate and enhance job descriptions and AI may have been used to create this description. The position description has been reviewed for accuracy and Dice believes it to correctly reflect the job opportunity.

Salary : $99,000 - $145,200

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