What are the responsibilities and job description for the Scientist I, Formulation Development position at Elektrofi?
Description
ABOUT ELEKTROFI
Elektrofi is revolutionizing the delivery of biologic therapies by giving patients the ability to control how they want to receive and benefit from life-changing medicines. Our breakthrough ultra-high concentration microparticle technology platform resolves the limitations associated with intravenously administered biologic therapies by enabling convenient at-home subcutaneous self-administration. With a focus on monoclonal antibodies, therapeutic proteins, and other biologics, we partner with companies to develop and commercialize our novel Hypercon™ formulations. We believe a patient-centered healthcare approach can lead to a healthier world. We are headquartered in Boston and innovate globally. We are Formulating the Future of Biologics™.
Position Summary
Elektrofi is seeking a motivated individual to join our biotech company as a Scientist I, Formulation Development to support the development of our novel Hypercon™ formulation platform. The individual will join a growing, multidisciplinary team of scientists/engineers and industry professionals.
Key Responsibilities
QUALIFICATIONS
EEOC Statement
Elektrofi provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.
To all agencies, please, no phone calls or emails to any employee of Elektrofi about this requisition. All resumes submitted by search firms/employment agencies to any employee at Elektrofi via email, the internet, or in any form and method will be deemed the sole property of Elektrofi unless such search firms/employment agencies were engaged by Elektrofi for this requisition and a valid agreement with Elektrofi is in place. If a candidate submitted outside of the Elektrofi agency engagement process is hired, no fee or payment of any kind will be paid.
All candidates must be legally authorized to work in the US
ABOUT ELEKTROFI
Elektrofi is revolutionizing the delivery of biologic therapies by giving patients the ability to control how they want to receive and benefit from life-changing medicines. Our breakthrough ultra-high concentration microparticle technology platform resolves the limitations associated with intravenously administered biologic therapies by enabling convenient at-home subcutaneous self-administration. With a focus on monoclonal antibodies, therapeutic proteins, and other biologics, we partner with companies to develop and commercialize our novel Hypercon™ formulations. We believe a patient-centered healthcare approach can lead to a healthier world. We are headquartered in Boston and innovate globally. We are Formulating the Future of Biologics™.
Position Summary
Elektrofi is seeking a motivated individual to join our biotech company as a Scientist I, Formulation Development to support the development of our novel Hypercon™ formulation platform. The individual will join a growing, multidisciplinary team of scientists/engineers and industry professionals.
Key Responsibilities
- Coordinate and execute drug product development activities to formulate a wide range of therapeutic biologic modalities into our proprietary Hypercon™ suspension using QbD principles.
- Utilize scaled-down process models and stress conditions to select formulations that optimize drug product performance, including protein stability and suspension physical properties.
- Independently design and execute hypothesis-driven experiments to drive continuous improvement of development workflows and enhance product understanding.
- Manage, compile and analyze data using analytical software.
- Represent the formulation development function on cross-functional CMC project teams internally and externally to our biopharmaceutical partners.
- Manage relevant method protocols, present findings and author reports to support regulatory submissions (IND, IMPD, BLA, etc.) and technology transfer.
QUALIFICATIONS
- PhD with 0 years, Masters with 2 or Bachelors with 4 years experience in Pharmaceutical Sciences, Chemical Engineering, Biochemistry, Material Science, Bioengineering, Physical Chemistry, Pharmaceutical Engineering, or a related field
- Demonstrated experience developing and optimizing protein formulations.
- Knowledge of protein biochemistry, protein stability and formulation design approaches to mitigate protein degradation mechanisms.
- Knowledge of rheology and flow characteristics of non-Newtonian fluids and relevant modeling.
- Understanding of statistical methods and design of experiments methodology.
- Familiarity with standard office software (MS Office, Teams, SharePoint, JMP) and electronic laboratory notebooks.
- Demonstrated good laboratory skills, organizational skills, and attention to detail.
- Ability to work in multi-disciplinary teams.
- Additionally, experience in one or more of the following areas of research is highly desirable
- High concentration protein formulation, long acting injectables, or lyophilized product development.
- Primary container selection, including compatibility and container closure integrity evaluations
- Development of pre-filled syringes and other combination products.
EEOC Statement
Elektrofi provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.
To all agencies, please, no phone calls or emails to any employee of Elektrofi about this requisition. All resumes submitted by search firms/employment agencies to any employee at Elektrofi via email, the internet, or in any form and method will be deemed the sole property of Elektrofi unless such search firms/employment agencies were engaged by Elektrofi for this requisition and a valid agreement with Elektrofi is in place. If a candidate submitted outside of the Elektrofi agency engagement process is hired, no fee or payment of any kind will be paid.
All candidates must be legally authorized to work in the US