Director, Controller

About EGenesis
eGenesis is a clinical-stage biotechnology company developing human-compatible engineered organs to address the severe global organ shortage. The Company’s proprietary genome engineering platform enables extensive, multiplex gene edits to remove key biological barriers, add protective human transgenes, and inactivate endogenous retroviruses. EGEN-2784, a genetically engineered porcine kidney, is the Company’s lead program and is currently being evaluated in a multi-patient Expanded Access study at MGH. eGenesis is headquartered in Cambridge, MA.

Position Summary
eGenesis, Inc is seeking a highly motivated and experienced Senior Director, Controller to lead the company’s accounting and financial reporting functions during a pivotal period of growth. Reporting to the VP, Finance, this leader will own the integrity of eGenesis’ financial statements, direct the monthly and quarterly close process, lead the annual audit, and ensure the company’s accounting infrastructure scales with its ambitions. This is a high-visibility role that partners closely with senior leadership and the audit committee on complex accounting matters and cross-functional financial operations. This is a full-time role based in Cambridge, MA.

Primary Responsibilities

• Own the end-to-end financial close process, including general ledger, accounts payables, and accruals, delivering accurate and timely monthly, quarterly, and annual financial statements in compliance with U.S. GAAP
• Serve as the company’s primary technical accounting resource, researching and documenting positions on complex transactions including collaboration agreements, equity instruments, clinical trial accruals, in-process R&D, and lease accounting
• Lead preparation and maintenance of financial statements and supporting schedules, ensuring disclosures are accurate, complete, and audit-ready
• Direct the annual financial statement audit and quarterly review processes; manage auditor relationships, PBC schedules, and audit timelines
• Oversee federal, state, and local tax compliance and filings in coordination with external tax advisors; manage tax provisions and ensure timely filing of all required returns
• Design, implement, and maintain a robust internal control environment appropriate for a company operating under public company accounting standards
• Administer equity accounting in coordination with legal and external stock plan administrators; ensure accuracy of stock-based compensation expense and capitalization table reporting
• Manage NetSuite as the system of record, partnering with FP&A on chart of accounts governance, reporting configuration, and process improvements
• Build and develop a high-performing accounting team; hire, mentor, and retain talent as the company grows
• Partner with the VP, Finance on board and audit committee financial materials, technical accounting memos, and ad hoc analytical support as needed
• Support the VP, Finance with account-level historical input for the long-range financial plan and investor-facing financial narratives
  
  
  
  
  

Basic Qualifications

• Bachelor’s degree in Accounting or Finance required; CPA required
• 10 years of progressive accounting experience, including at least 3 years in a Controller or Assistant Controller capacity; Big 4 public accounting experience strongly preferred
• Public company accounting experience required, including demonstrated ownership of financial statement preparation and audit management under public company reporting timelines
• Biotech or life sciences industry experience required; familiarity with clinical-stage accounting (CRO accrual methodology, collaboration agreement) strongly preferred
• Hands-on proficiency with NetSuite required
• Deep technical accounting knowledge of U.S. GAAP, with particular facility in ASC 718 (stock-based compensation), ASC 842 (leases), and equity accounting
• Demonstrated ability to build and document internal controls in a dynamic, high-growth environment
• Strong communicator with the ability to translate complex accounting positions clearly for non-accountants, auditors, and senior leadership
  
  
  
  
  

Base pay range for this job is $180,500-$233,500.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.