Demo

Senior MES Engineer

DP Professionals Inc
Raleigh, NC Full Time
POSTED ON 3/28/2026
AVAILABLE BEFORE 4/26/2026
DPP is seeking a Senior MES Engineer for a direct hire opportunity with a Raleigh, NC company that provides advanced engineering solutions for global industries.
 
Position overview:
  • Senior technical leader responsible for designing and delivering MES solutions in life sciences manufacturing
  • Acts as MES Solution Architect and Technical Lead
  • Works directly with customers and leads WM engineering teams
  • Success is measured by delivery quality, project profitability, and repeat customer work 
Key responsibilities:
  • Design, configure, and deploy enterprise MES solutions
  • Lead MES projects end‐to‐end: concept, design, build, test, validation, and commissioning
  • Develop MES strategy that improves compliance, uptime, and efficiency
  • Lead engineers and mentor junior staff
  • Own technical decisions and guide customers
  • Manage or support projects up to $1M, including:
    • Plans, schedules, budgets, and status reporting
    • Risk and issue resolution
    • Team coordination
  • Serve as Project Manager on smaller engagements when needed 
Technical focus:
  • Enterprise MES platforms (PAS‐X, Syncade, PharmaSuite, POMS, Sepasoft, etc.)
  • Electronic Batch Records (EBR)
  • Life sciences regulations and validation
  • Integration with:
    • ERP
    • SCADA / Historian
    • LIMS, QMS, CMMS
  • On‐prem and cloud architectures
  • Databases (SQL, Oracle) 
Required knowledge, skills, and abilities:
  • Bachelor’s degree in Engineering, Computer Science, or Applied Sciences
  • 7 years of MES experience in life sciences
  • Strong knowledge of:
    • cGMP
    • 21 CFR Part 11
    • GAMP5, ISA‐88, ISA‐95
  • Proven leadership and customer‐facing experience
  • Strong written and verbal communication skills
  • Willing to travel up to 25% 
Ideal fit:
  • Senior MES engineer ready to lead technically and influence customers
  • Comfortable balancing hands‐on design with leadership and project ownership
  • Strong in regulated manufacturing environments 
About the company:
Our client is an engineering and architectural firm specializing in system integration and advanced engineering solutions for a diverse range of global industries.
  • 100% employee‐owned (ESOP)
  • 40 years in business
  • ENR Top 500 firm and top system integrator 
Interested? Learn more:
Click the apply button or contact our recruiter Sarah at  to learn more about this position (#26-00257).

Authorized US Worker - s and those authorized to work in the US are encouraged to apply. We are unable to sponsor at this time. EOE/AA/V/D

DP Professionals (DPP) is a premier, full-service staffing and recruiting firm that specializes in the placement of highly qualified knowledge workers in both contingent and direct hire opportunities. Located in "famously hot" Columbia, SC, DPP is a certified Woman-owned Small Business Enterprise (WBE and WOSB) with more than 25 years in the staffing industry.

Salary : $160,000 - $170,000

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