Bioinformatics Team Leader, Genomics & Fieldable Analytics

About DSI

Dominion Sciences Initiative, LLC (DSI) is a growing Maryland-based company led by experienced federal biomedical scientists and program leaders. Our work spans genomics, infectious-disease diagnostics, biosurveillance, advanced sensing, clinical research, environmental surveillance, CBRNE, and federal biomedical R&D.

The Position

DSI is seeking an experienced Bioinformatics Team Leader to lead computational biology, genomic analysis, pipeline development, scientific software, and fieldable bioinformatics activities.

This key-personnel position combines technical depth with leadership of a multidisciplinary bioinformatics team supporting pathogen genomics, biosurveillance, emerging-threat response, and operational analytical capabilities.

Responsibilities

• Lead and mentor bioinformatics analysts and engineers.
• Provide technical direction for genomics, metagenomics, pathogen characterization, and infectious-disease surveillance.
• Develop, validate, benchmark, and maintain automated bioinformatics pipelines.
• Oversee genome assembly, annotation, taxonomic profiling, phylogenetics, and molecular epidemiology.
• Guide analysis of clinical, environmental, wastewater, animal, vector, bacterial, viral, and bacteriophage samples.
• Lead testing and evaluation of bioinformatics software and methods for DoD applications.
• Develop or improve fieldable bioinformatics software and analytical workflows.
• Apply AI and machine-learning methods to biological and genomic data where appropriate.
• Establish reproducible methods, documentation, source-control practices, testing, and quality standards.
• Support field demonstrations, training, international laboratory partners, and analytical reach-back.
• Prepare technical reports, presentations, documentation, and scientific products.
• Work directly with laboratory scientists, epidemiologists, Government researchers, and international partners.

Required Qualifications

• Master's degree or PhD in Bioinformatics, Computational Biology, Computer Science with biological/bioinformatics experience, or a closely related discipline.
• At least 10 years of hands-on bioinformatics experience.
• Demonstrable multiyear experience in computer science, genomics, bioinformatics, and computational biology.
• Expert programming skills in Python and/or R and experience with languages such as Perl or Java.
• Extensive experience with NGS analysis.
• Familiarity with platforms such as Illumina MiSeq, NextSeq, NovaSeq, iSeq or MiniSeq; Oxford Nanopore MinION or GridION; and/or PacBio.
• Experience leading bioinformatics, computational-science, or scientific software teams.
• Strong communication, leadership, documentation, and problem-solving skills.
• Ability to perform under deadlines and support potentially austere field environments.
• Ability and willingness to travel nationally and internationally.
• U.S. citizenship and ability to satisfy applicable Government security requirements.

Preferred Qualifications

Experience with microbial/pathogen genomics, metagenomics, AI/ML, automated workflows, fieldable/disconnected bioinformatics, HPC/cloud computing, international laboratory support, biosurveillance, wastewater surveillance, DoD/NMRC research, and training technical personnel is particularly valuable.

Why Join DSI

This position provides an unusual opportunity to help build DSI's bioinformatics capability, not simply manage an existing production team.

The successful candidate can have direct influence over technical practices, analytical tools, recruiting, future hires, internal R&D, proposal strategy, and the direction of DSI's broader genomics and computational-biology portfolio.

As DSI grows, this role can develop into broader technical, program, and corporate scientific leadership.

Compensation and Benefits

The anticipated salary range is $140,000–$180,000 annually.

DSI intends to provide employer-subsidized medical coverage, access to dental and vision coverage, a 401(k) with employer contribution, paid time off, paid holidays, and required workers' compensation coverage. Final terms will be provided with any contingent offer.

Application

Please submit a current resume or CV emphasizing bioinformatics leadership, genomics, NGS, programming, pipeline/software development, team leadership, infectious-disease experience, citizenship, and clearance status if applicable.

This position is contingent upon contract and subcontract award and applicable Government approvals and onboarding requirements.

• Dominion Sciences Initiative, LLC is an equal opportunity employer.