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Principal Investigator

Denali Health
Minneapolis, MN Remote Full Time
POSTED ON 10/23/2026
AVAILABLE BEFORE 12/23/2026

About Denali:

Denali Health is seeking an experienced Physician to serve as Principal Investigator (PI) for our dedicated clinical research sites. The PI will be responsible for ensuring the integrity and patient safety of the clinical trials. The ideal Principal Investigator will have a strong background in clinical research, a commitment to upholding the highest ethical standards, and a passion for advancing medical science.

Key Benefits of the Opportunity:

Flexible Work Arrangements: Denali Offers Investigators flexible scheduling

Adaptable Scheduling: Commitment typically requires 5-10 hours per week

Streamlined Operations: Denali's world-class operations, regulatory, compliance, and clinical services infrastructure to make being an investigator as smooth as possible.

Key Responsibilities:

Regulatory Documentation: Review and sign essential regulatory documents

During/Post Study Responsibilities: Oversee patient safety and required clinical assessments.

Study Conduct & Subject Management: Provide medical oversight; our team manages daily operations.

Safety Reporting & Documentation: Assess adverse events with full documentation support.

Qualifications:

Education:

  • MD or DO degree required. A PhD, in a related field may be considered.
  • Board certification in a relevant medical specialty is preferred

Experience:

  • Minimum of 2 years of experience as a Principal Investigator or Sub-Investigator in clinical trials.

Why Denali Health?

At Denali Health, we are committed to accelerating therapeutic innovations by breaking the bottlenecks in research and bridging the gap from bench to market. Denali Health promotes an inclusive environment that fosters independence & career growth. Join our team and be part of a dynamic organization that values integrity, innovation, and excellence in clinical research.

Denali Health is an equal-opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

Salary.com Estimation for Principal Investigator in Minneapolis, MN
$94,602 to $125,788
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