Bioinformatics Engineer

Senior Software Engineer - Bioinformatics 


We are seeking an experienced Senior Software Engineer to start as a consultant to help drive the evolution of a large-scale clinical bioinformatics platform. This role combines software engineering, systems optimization, and bioinformatics expertise to support the development of high-throughput genomic analysis workflows in a regulated production environment.

As a key member of a small engineering team, you will take ownership of designing, building, testing, and maintaining critical software components that support genomic data processing and analysis. This is a hands-on engineering role focused on production systems rather than research.

• Design, develop, test, and deploy scalable software solutions supporting genomic data analysis workflows.
• Identify performance bottlenecks and implement optimizations across complex data-processing pipelines.
• Develop new analytical modules and enhance existing systems to improve functionality, reliability, and throughput.
• Automate operational and development processes to increase efficiency and scalability.
• Translate business and operational requirements into technical designs and production-ready solutions.
• Ensure software quality through testing, validation, documentation, and adherence to engineering best practices.
• Collaborate with cross-functional stakeholders to understand workflow requirements and system dependencies.
• Contribute to architecture decisions, technical standards, and long-term platform improvements.

• Master's degree in Computer Science, Computational Biology, Mathematics, Engineering, or a related technical field.
• 3 years of professional software engineering experience.
• Strong experience building and maintaining production-grade software systems.
• Advanced Python development skills, including software architecture, package management, testing frameworks, and design patterns.
• Strong Linux and shell scripting experience.
• Experience working with bioinformatics workflows and genomic data formats such as FASTQ, BAM, CRAM, and VCF.
• Familiarity with next-generation sequencing technologies and variant analysis methodologies.
• Experience designing and supporting complex data-processing systems.
• Strong understanding of software development lifecycle practices, testing strategies, and code quality standards.

• PhD in a related technical discipline.
• 5 years of industry experience.
• Experience with modern web technologies such as TypeScript.
• Experience with systems programming languages such as Rust or C .
• Experience with document-oriented and relational databases, including schema design and data migration activities.
• Experience working in highly regulated, quality-focused environments.

• Strong problem-solving and analytical skills.
• Ability to work independently and take ownership of critical projects.
• Excellent communication and collaboration abilities.
• A passion for building reliable, scalable systems that support meaningful real-world outcomes.
• A mindset focused on quality, performance, and continuous improvement.

For immediate consideration, please email a resume to Kenny at Kwilliams@daleyaa.com