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Supervisor/Manager, Technical Operations (In Vivo)

Crown Bioscience San Diego Inc.
San Diego, CA Full Time
POSTED ON 12/9/2025
AVAILABLE BEFORE 2/9/2026
Job Summary: The Technical Operations Supervisor/Manager will lead and oversee the daily operations of the in vivo technical team, ensuring high-quality execution of preclinical studies and technical procedures. This role will be responsible for performing daily assigned hands-on work to execute the assigned daily tasks. This role will also provide team supervision, training and scheduling, while maintaining compliance with regulatory and quality standards. Responsibilities: • Lead and manage technical staff performing complex in vivo procedures. • Perform daily in vivo oncology studies • Oversee scheduling and resource allocation for client studies and internal R&D projects. • Develop and implement training programs for new and existing staff. • Collaborate with scientific and operational leadership to set short- and long-term goals. • Ensure adherence to SOPs, animal welfare regulations, and QA oversight. • Support development and validation of new research models and techniques. • Provide technical guidance and troubleshooting for study execution. • Maintain high standards of documentation, data integrity, and communication. • Foster a collaborative and inclusive team environment through mentorship and team-building activities. Minimum Requirements: • Bachelor’s degree in scientific discipline (e.g., biology, pharmacology). • 5 years of experience in vivo studies, preferably in a CRO or preclinical research setting with expertise including but not limited to the following skillsets: Tumor measurement using clippers; Dosing through IN, PO, IP, SC, IT, IM; Blood collection through cheek, tail snip, tail vein; Tissue collection of organs, lung inflation, muscle isolation, brain dissections; Tumor inoculation via different routes (subcutaneously or orthotopically). • Strong organizational, communication, and problem-solving skills. • Experience with scheduling and managing complex technical workflows. Preferred Requirements: • Advanced Degree (Master’s degree or PhD in a relevant field) • Experience in oncology-related animal studies. • Proficiency in project management tools and Microsoft Office Suite. • Experience in using Study Log, Smartsheet and ELN • Prior experience developing and validating new vivo models. • Prior management experience • Ability to work under pressure and meet tight deadlines • Familiarity with regulatory and quality systems (e.g., GLP, IACUC). Salary Range: $78,000 - $105,000 This salary (or salary range) is merely an estimate and may vary based on an applicant’s skills and prior relevant experience. EEO Statement: Crown Bioscience is committed to a diverse and inclusive workplace. Crown Bioscience is an equal opportunity employer and does not discriminate based on race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status. Crown Bioscience, a JSR Life Sciences company, is a global contract research organization (CRO) providing discovery, preclinical, and translational platforms to advance oncology and immuno-oncology. Known for their high quality and expansive in vivo, in vitro, and ex vivo preclinical models, they partner with their clients to quantify the efficacy and pharmacological profile of their drug candidate before they move into the clinic. The company is the only preclinical CRO to provide tumor organoid services utilizing HUB technology and has the world’s largest commercially available PDX collection. Additionally, further services available in the areas of high content imaging and a 3D Ex Vivo Patient Tissue Platform, provide greater insights into complex disease pathophysiology. A range of biomarker analysis and applied genomics services are also available to optimize therapeutic benefit. Crown Bioscience helps to deliver superior drug candidates to ensure that patients get the right treatment at the right time. Founded in 2006, Crown Bioscience has 12 facilities in the US, Europe, and APAC. Find out more: www.crownbio.com Crown Bioscience is committed to a diverse and inclusive workplace. Crown Bioscience is an equal opportunity employer and does not discriminate on the basis of race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status. If you have a disability or special need that requires accommodation, please let us know: jobs@crownbio.com Headhunters and recruitment agencies may not submit resumes/CVs through this website or directly to managers. Crown Bioscience does not accept unsolicited headhunter and agency resumes. Crown Bioscience will not pay fees to any third-party agency or company that does not have a signed agreement with Crown Bioscience.

Salary : $78,000 - $105,000

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