Scientist - Biologics

To Discuss more about this job opportunity, please reach out to Deepak Arya (LinkedIn URL www.linkedin.com/in/deepak-arya-8a79aa22a/), email your updated resume at Email deepak.arya@collabera.com. Thank you!

Pay Range: $40 to $50 an hour.

Client Industry: Pharmaceutical

Job Mode: Onsite

Contract Duration: 12 Months Contract, with potential extension based on performance and business

Job Summary:

The Scientist will support early stage developability assessments of therapeutic biologics, identifying formulation, stability, and manufacturability risks to guide candidate selection and development decisions. The role involves conducting laboratory characterization studies across diverse biologic molecules, including monoclonal antibodies, bispecific antibodies, antibody drug conjugates, and fusion proteins. The scientist will evaluate protein stability under different solution conditions and manufacturing related stresses. The position requires collaboration with cross functional scientific teams and clear communication of experimental findings through technical reports and presentations.

Key Responsibilities:

• Conduct candidate screening and characterization studies to evaluate the developability of therapeutic biologics.
• Assess conformational stability using differential scanning fluorimetry and differential scanning calorimetry, along with solution viscosity measurements.
• Evaluate chemical and physical stability under varying pH, ionic strength, temperature, and light conditions.
• Investigate the impact of manufacturing related stresses, including freeze thaw cycles, mixing, filtration, filling, and lyophilization.
• Prepare technical reports and presentations communicating scientific findings, potential risks, and development recommendations.
• Review scientific literature and contribute to new scientific initiatives and improvements in experimental methods.

Required Qualifications:

• Bachelor of Science with at least 4 years of relevant experience or Master of Science with at least 2 years of relevant experience in Biochemistry, Chemistry, Pharmaceutical Sciences, Chemical Engineering, Bioengineering, or a related discipline.
• Hands on laboratory experience in biologics characterization and analytical testing.
• Experience with analytical techniques such as HPLC, UPLC, SEC, DLS, DSF, DSC, or UV Vis spectroscopy.
• Understanding of protein structure, stability, chemical and physical degradation, and characterization.
• Strong scientific communication, technical writing, and documentation skills.
• Ability to work independently, manage changing priorities, and collaborate with cross functional teams.

Preferred Qualifications:

• Experience in formulation development, protein stability, or developability assessment of therapeutic biologics.
• Familiarity with capillary electrophoresis, icIEF, and particle analysis.
• Knowledge of monoclonal antibodies, bispecific and multispecific antibodies, antibody drug conjugates, and fusion proteins.
• Experience evaluating protein degradation pathways and improving experimental approaches.

Benefits: The Company offers the following benefits for this position, subject to applicable eligibility requirements: medical insurance, dental insurance, vision insurance, 401(k) retirement plan, life insurance, long term disability insurance, short term disability insurance, paid parking/public transportation, (paid time , paid sick and safe time , hours of paid vacation time, weeks of paid parental leave, paid holidays annually AS Applicable)