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Bioconjugation Scientist

Cogent Scientific
South San Francisco, CA Full Time
POSTED ON 11/25/2025
AVAILABLE BEFORE 1/24/2026

Cogent Scientific, an insourced contract research organization, is looking for the right people to accomplish our Mission: to build lasting partnerships that enable the life sciences industry to accelerate discovery and innovation in research and manufacturing.  We can offer you the chance to build on your skills and knowledge while working among experts in their fields and with cutting-edge instrumentation.

 

Cogent Scientific offers competitive pay (with relocation bonus as needed), attractive benefits (such as medical/dental/vision insurance; 401(k); parental leave; PTO and paid holidays; etc.) and an exciting work environment.  We aim to recruit the best people who stand out among their peers and embody our Core Values:

 

  • Client Focused: We only succeed when our clients succeed.
  • Outstanding: We deliver meticulous results through outstanding performance.
  • Good: We act ethically and morally.
  • Employee-Centric: We honor and support our employees.
  • Nimble: We are prepared to adapt in an ever-changing industry.
  • Team-Oriented: We collaborate with each other and with our clients.

 

We currently have a role available for Bioconjugation Scientist.

 

Job duties include, but are not limited to:

  • Preparing, purifying, and characterizing the high-quality antibody-conjugates (ADCs, ARCs, DACs etc.) with a high degree of independence in support of discovery and development of programs.
  • Implementing state of the art bioconjugation technologies (cysteine, lysine, site-specific and other) and utilizing other bio-orthogonal chemistries to generate bioconjugates.
  • Developing purification strategies (up to 100 mg) with affinity, ion-exchange, hydrophobic interaction, size exclusion, and tangential flow filtration.
  • Maintaining thorough documentation of experimental procedures in electronic notebook or database, writing of reports and technical documents.
  • Engaging with multidisciplinary project teams to execute and interpret experiments.
  • Participating and presenting periodic updates and reports to management team.

 

Job requirements include, but are not limited to:

  • A minimum of a master’s degree in chemistry, biochemistry, or other related scientific discipline with a record of minimum 2 years lab-based independent research experience is required. PhD degree with relevant experience is preferred.
  • Extensive expertise in using state-of-the-art conjugation methods and handling of potent linker-payloads.
  • Experienced in ADC characterization methods, including UV-Vis, SEC, HIC, RP, IEX, cIEF, and LC-MS.
  • Excellent communication skills – verbal and written.
  • Works well both as a team and as an individual.
  • Demonstration of excellent team player skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions. The ideal candidate will be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery.  

 

This job posting will close by 2/1/2026 or when a candidate is identified, whichever comes first.

Salary.com Estimation for Bioconjugation Scientist in South San Francisco, CA
$134,577 to $165,361
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