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Associate Scientist ,In Vivo Pharmacology

citytherapeutics
Cambridge, MA Full Time
POSTED ON 5/28/2026
AVAILABLE BEFORE 7/28/2026

The Associate Scientist, In Vivo Pharmacology role will play a key role in helping advance City’s platform technology and screening potential siRNA therapeutics in vivo. The Associate will support in vivo pharmacology studies by assisting with animal handling, dosing, sample collection, and data recording. This entry-level role is ideal for candidates seeking hands-on experience in preclinical research and drug discovery.

 

 

 

Responsibilities: 

  • Assist in the execution of in vivo studies involving mice and rats.
  • Prepare study materials and maintain accurate and timely data recording.
  • Dose animals via various routes (IP and SC), monitor body weights and general health, perform euthanasia, and harvest tissues.
  • Assist scientists in advanced surgical and dosing procedures.
  • Maintain inventory of supplies.
  • Assist in performing downstream molecular analysis of tissues by RT-qPCR, western, and/or ELISA.
  • Work collaboratively in a multi-team environment.  

 

Qualifications:

  • B.S. in Biology or related field plus experience scruffing/handling and comfortable working with mice and/or rats.
  • Experience such as dosing IP, SC, blood collections and tissue collection a plus.
  • Experience doing ex vivo analysis techniques such as RNA and protein isolation, RT-qPCR, western blot, and/or ELISA a plus.
  • Strong attention to detail, passion and ability to learn, and take initiative.

 

 

 

 

 

City Therapeutics is accepting resumes/CVs from direct applicants only. Recruitment Agency inquiries or submissions will not be accepted at this time.

Compensation: The base salary range provided reflects our current estimate of what we anticipate paying for this position. Your actual base salary will be based on several factors, including relevant skills, experience, internal equity, relevant education or training and market dynamics. In addition, this role is eligible for an annual cash bonus and equity compensation. City Therapeutics offers a comprehensive and competitive benefits package including medical, dental, vision, life insurance, health and dependent care FSA accounts, HSA/HRA accounts with company contributions, in addition to a 401(k) with competitive company match. Per Year Salary Range: $79,000 to $90,000

 

City Therapeutics is an Equal Opportunity and Affirmative Action employer committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

The Associate Scientist, In Vivo Pharmacology role will play a key role in helping advance City’s platform technology and screening potential siRNA therapeutics in vivo. The Associate will support in vivo pharmacology studies by assisting with animal handling, dosing, sample collection, and data recording. This entry-level role is ideal for candidates seeking hands-on experience in preclinical research and drug discovery.

 

 

 

Responsibilities: 

  • Assist in the execution of in vivo studies involving mice and rats.
  • Prepare study materials and maintain accurate and timely data recording.
  • Dose animals via various routes (IP and SC), monitor body weights and general health, perform euthanasia, and harvest tissues.
  • Assist scientists in advanced surgical and dosing procedures.
  • Maintain inventory of supplies.
  • Assist in performing downstream molecular analysis of tissues by RT-qPCR, western, and/or ELISA.
  • Work collaboratively in a multi-team environment.  

 

Qualifications:

  • B.S. in Biology or related field plus experience scruffing/handling and comfortable working with mice and/or rats.
  • Experience such as dosing IP, SC, blood collections and tissue collection a plus.
  • Experience doing ex vivo analysis techniques such as RNA and protein isolation, RT-qPCR, western blot, and/or ELISA a plus.
  • Strong attention to detail, passion and ability to learn, and take initiative.

 

 

 

 

 

City Therapeutics is accepting resumes/CVs from direct applicants only. Recruitment Agency inquiries or submissions will not be accepted at this time.

Compensation: The base salary range provided reflects our current estimate of what we anticipate paying for this position. Your actual base salary will be based on several factors, including relevant skills, experience, internal equity, relevant education or training and market dynamics. In addition, this role is eligible for an annual cash bonus and equity compensation. City Therapeutics offers a comprehensive and competitive benefits package including medical, dental, vision, life insurance, health and dependent care FSA accounts, HSA/HRA accounts with company contributions, in addition to a 401(k) with competitive company match. Per Year Salary Range: $79,000 to $90,000

 

City Therapeutics is an Equal Opportunity and Affirmative Action employer committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

 

Salary : $79,000 - $90,000

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