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Postdoctoral Fellow - Vascular Biology, Diabetes and Cancer

City of Hope
Duarte, CA Full Time
POSTED ON 5/24/2026
AVAILABLE BEFORE 6/30/2026
Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

A Postdoctoral researcher opportunity is available in the laboratory of Dr. Zhen Bouman Chen, a leading expert in the field of vascular biology and diabetes complications and Co-Director of the Cardiovascular Research Center at the Arthur Riggs Diabetes Metabolism Research Institute of City of Hope.

Built upon her interdisciplinary training in medicine, vascular biology, bioengineering, and data science, Dr. Chen leads an active research program focused on epigenetics, RNA and chromatin biology and endothelial stress response. Her team integrates innovative high-throughput sequencing technologies, bioinformatics approaches, and multi-scale models to elucidate RNA-mediated endothelial biology in the context of diabetes. In parallel, the lab emphasizes translational research to identify novel diagnostic and therapeutic targets and to develop innovative strategies that can be advanced toward clinical application. Dr. Chen is passionate about mentorship and peer support and Chairs the Women Leadership Committee of the Arteriosclerosis, Thrombosis, and Vascular Biology Council of the American Heart Association.

For more information on Dr. Chen’s research please visit here.

As a successful candidate, you will:

  • Conduct research on NIH-funded and other externally or internally supported projects focused on vascular biology, diabetes (and its complications), and/or cancer.
  • Collaborate with a multidisciplinary team including lab technicians, bioinformaticians, bench scientists, statisticians, and physician-scientists to:
  • Perform experiments using cell culture, organoids, animal models, and human tissues
  • Conduct bioinformatics analyses of high-throughput sequencing data
  • Interpret and present findings through scientific publications and presentations at national and international conferences
  • Be strongly encouraged and supported to apply intramural and extramural funding for career development
  • Mentor junior researchers, students, and interns

Your qualifications should include:

  • A M.D. and/or Ph.D. degree in life sciences
  • Preferred research in one or more of these areas: cardiovascular biology, metabolic disease, cancer or cancer immunology, neurodegenerative diseases and/or aging

Preferred technical experience in one or more of the following areas:

  • Mouse handling and metabolic phenotyping
  • Microsurgical techniques (e.g., dissection, ligation, suturing)
  • Organoids and 3D culture systems
  • Vascular/endothelial biology or stem cell biology
  • Single cell biology, scRNA/snRNA/scATAC-sequencing
  • Immunohistochemistry and tissue processing
  • Immunology, flow cytometry, and imaging-based analyses
  • High-throughput sequencing data analysis and bioinformatics
  • Nanomedicine and targeted delivery systems
  • Machine learning and artificial intelligence

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.

Salary : $34 - $37

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