Research Scientist

Part-Time Research Scientist (Wet Lab Lead)Location: Premier NYC Life Science IncubatorCompany: Circadian OSCommitment: Part-time (10–20 hrs/week)About UsCircadian OS is building a next-generation platform that combines personalized phototherapy with biomarker-driven insights to optimize circadian biology for improved therapeutic outcomes in oncology and beyond. We are expanding our R&D capabilities and seeking our first wet-lab scientist to establish foundational experimental workflows and build the company’s internal assay capabilities.Role OverviewWe are seeking a highly motivated, independent Part-Time Research Scientist with expertise in primary cell isolation, gene expression analysis, and molecular assays. This individual will establish Circadian OS’s wet lab within a premier NYC incubator, lead initial assay development, and operationalize the analytical workflows that will underpin our biomarker platform. This is a unique opportunity for a self-starter who thrives in early-stage environments and wants to directly shape the company’s experimental and analytical infrastructure.RequirementsKey ResponsibilitiesLaboratory Setup & OperationsEstablish and organize company lab space within a premier NYC incubator.Source, evaluate, and order laboratory equipment, reagents, and consumables.Coordinate with incubator lab management to ensure compliance with safety and operational requirements.Develop and maintain SOPs and documentation for experimental workflows, equipment use, and sample handling.Assay Development, Execution & TroubleshootingIsolate monocytes from fresh human blood using standard protocols (e.g., Ficoll, adherence, MACS).Perform high-quality RNA extractions and ensure sample integrity.Execute gene expression profiling using established RNA expression methods (e.g., qPCR, targeted panels, RNA expression profiling workflows). Experience with NanoString is a plus but not required.Set up, optimize, and validate company-specific assays, including troubleshooting experimental issues and improving protocols.Data Analysis & BenchmarkingEstablish analytical workflows to process gene expression data, including quality control and normalization.Validate and benchmark expression results across replicates, conditions, and platforms.Compile, interpret, and present results to scientific leadership.Contribute to experimental design and next-step recommendations based on analytical insights.Cross-Functional CollaborationWork closely with leadership to align lab activities with scientific and product development goals.Communicate progress, challenges, and data clearly and proactively.Support planning for lab growth, additional assay technologies, and future R&D expansion.QualificationsMaster’s or PhD in Molecular Biology, Immunology, Cell Biology, Bioengineering, or a related field.Hands-on experience isolating monocytes from blood is required.Hands-on experience performing RNA extractions is required.Experience with RNA expression profiling methods (e.g., qPCR, targeted panels). NanoString experience is a plus but not required.Strong troubleshooting skills and comfort operating independently as the first wet-lab hire.Prior experience setting up or running a small research lab highly preferred.Strong organizational, experimental design, and communication skills.Familiarity with incubator environments and shared lab operations is a plus.Experience with basic computational analysis of gene expression data (R, Python, or vendor software).BenefitsCompensationCompensation range (required by NY law): $40–$70 per hour, depending on experience and qualifications.What We OfferFlexible part-time schedule (10–20 hrs/week).Opportunity to establish foundational wet-lab capabilities without the demands of a full-scale lab buildout.Direct impact on experimental strategy, biomarker development, and early R&D priorities, with a scope appropriate for a part-time role.

Salary : $40 - $70