What are the responsibilities and job description for the Senior Scientist (Branford, CT) position at CEDENT?
We're hiring a Senior or Principal Scientist to join our Biotherapeutics team's collaborative group focused on designing and advancing first-in-class immune-engaging biologics. If you’re a protein engineer who thrives in the lab and wants your work to move swiftly toward patients, this role offers real opportunity, purpose, and scientific challenge.
What You’ll Work On
What You’ll Work On
- Design and optimize novel antibody and bispecific formats that power our next-generation immunotherapies
- Lead antibody engineering from idea to construct to bench — including expression, purification, and characterization
- Improve key attributes like affinity, stability, specificity, and PK using modern tools and data
- Drive developability assessments with platforms like SPR, BLI, DSC, DLS, ciEF, and LC-MS
- Collaborate across functional teams to support candidate selection and preclinical development
- Develop and refine functional assays for biologic characterization
- Present findings in a clear, compelling way to multidisciplinary teams
- Mentor junior scientists (if interested) and help shape our growing discovery organization
- PhD in Biochemistry or a related field and 5 years of industry experience (or)
- MS with 10 years in antibody engineering roles
- Strong foundation in antibody structure–function relationships and biologics drug development
- Expertise in protein design, expression, purification, and biophysical characterization
- Deep experience with bispecific or multispecific formats and familiarity with T cell engagers
- Working knowledge of structure–activity relationships and/or molecular modeling is a plus
- Experience with mammalian expression systems (e.g., CHO/HEK), cell-based assays, or phage/yeast display is valuable
- Strong communication, data interpretation, and cross-functional collaboration skills
- Direct impact: Your ideas and experiments will influence platform design and help shape clinical programs
- Cutting-edge science: Work on a truly novel immunotherapy approach in a scientifically rigorous, fast-moving environment
- Personal growth: Take on visible, high-impact projects in a startup culture where contributions are recognized and development is supported
- Collaborative culture: Join a tight-knit, mission-driven team that values open communication, learning, and teamwork
- Mission with meaning: Be part of a company working to give more patients real hope in the fight against cancer