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Postdoctoral Fellow, Laboratory of Dr. Diana Hargreaves

Career Opportunities
La Jolla, CA Full Time
POSTED ON 7/25/2026
AVAILABLE BEFORE 9/25/2026

Job Summary

The Hargreaves lab aims to understand how epigenetic processes, and particularly SWI/SNF chromatin remodeling, regulate immune cell differentiation and function and how mutations in SWI/SNF subunits give rise to diseases such as cancer. In particular, the lab is examining how SWI/SNF complexes collaborate with transcription factors and other epigenetic processes to license enhancer activation in response to developmental and environmental signals. Further, the lab is investigating the therapeutic mechanisms underlying mutations in SWI/SNF complex subunits which occur at high frequency in human cancer, based on our recent evidence that these mutations result in improved responsiveness to immunotherapy via upregulation of immune signaling.

The ideal candidate will be a molecular and cellular biologist who has experience in biochemistry, molecular biology techniques, next-generation sequencing, flow cytometry, or tumor-immune studies. Ideal candidates should be intellectually curious, highly productive, driven to uncover new and impactful biology, and enjoy working in a committed and diverse team. The postdoc will join a vibrant group of molecular biologists, cell biologists and computational biologists to work in a team that is determined to address the role of epigenetic regulation of cancer biology and inflammation.

Education

PhD in Biological Sciences

Job location is in Salk Main Campus

What We Can Offer

The full postdoctoral salary range for wet lab opportunities is $70,500-$78,000 (see below). This range covers the entire postdoctoral training period; recent Ph.D. graduates should expect an offer at or close to $70,500 (minimum of the salary range). Salk Institute provides pay ranges representing its good faith estimate of what the institute reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location, and external market pay for comparable jobs.

Experience Level/Tier Salk Postdoc Salary
0 $70,500
1 $72,000
2 $73,500
3 $75,000
4 $76,500
5 $78,000

Benefits

Salk Institute offers competitive benefits, including medical, dental, vision, retirement, paid time off, tuition reimbursement, patient advocacy services, and transit/parking program.

Salk Values

The Salk Community, both scientists and administrators, worked together to define values that we believe support Salk’s pursuit of excellence. To be truly the best scientific institution requires not only incredible discoveries, but a common understanding of how we should work together to enable those discoveries.

The acronym “I CARE” provides a simple way to remember each of the values and reminds each of us of the importance of what we do each day.

Equal Employment Opportunity Statement

The Salk Institute for Biological Studies is an Equal Opportunity Employer and is committed to providing equal access to opportunities for students, employees, applicants for employment and other visitors. Salk has also adopted and maintains a policy to encourage professional and respectful workplace behavior and prevent discriminatory and harassing conduct in our workplace.

Accordingly, the Institute prohibits harassment and discrimination in employment on the basis of, and considers all qualified applicants for employment without regard to, actual or perceived race (race is inclusive of traits associated with race, including, but not limited to, hair texture and protective hairstyles. Protective hairstyles include, but not limited to, such hairstyles as braids, and twists), color, religion, religious creed (including religious dress and grooming practices), national origin, ancestry, citizenship, physical or mental disability, medical condition (including cancer and genetic characteristics), genetic information, marital status, age, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), reproductive health decision making, gender, gender identity, gender expression, sexual orientation, veteran and/or military status (disabled veteran, veteran of the Vietnam era, other covered veteran status), political affiliation, and any other status protected by state or federal law.

Discrimination is prohibited with any intersectionality of the above-mentioned characteristics, including:

  1.  Any combination of characteristics.
  2.  A perception that the person has any of the characteristics or any combination of those characteristics.
  3.  A perception that the person is associated with a person who has, or is perceived to have, any of those characteristics or any combination of those characteristics.

IND123

Salary : $70,500 - $78,000

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