Senior Scientist, In Vivo - Cardiometabolic-Chronic Kidney Disease

Description

The Cardiovascular-Renal-Metabolic Diseases Research (CRMDR) team in Ridgefield, CT has delivered numerous first-in-class therapeutics into clinical development in the last decade in disease areas spanning Chronic Kidney Disease, Liver Cirrhosis, and Portal Hypertension. In the coming decade, our ambition will address the wider-reaching, interconnected cardio-renal-metabolic space. Innovation at Boehringer Ingelheim capitalizes on synergies with adjacent therapeutic areas, multi-disciplinary project teams, academic collaborations, and is strengthened by teaming up with CRMDR colleagues in Biberach, Germany. People and culture are the drivers of success, and this engine is fueled by the intention to build enriching careers on the way as we deliver novel drugs.

The Translational Pharmacology group within Cardiovascular-Renal-Metabolic Diseases Research (CRMDR) is seeking a highly motivated, team-oriented Senior Scientist to join our team in Ridgefield, CT. The qualified candidate will lead in vivo research efforts focusing on techniques and studies that elucidate cardiovascular function using preclinical models spanning kidney, heart, liver, and metabolic disease. This is a hands-on, lab-based position requiring candidates to have in-depth technical knowledge to lead science in a collaborative, multi-disciplinary research environment.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Duties & Responsibilities

• Independently design and perform scientific experiments, including implementing new and innovative methodologies (e.g. echocardiography) to enable drug discovery projects
• Build in vivo models and technical capabilities of cardiorenal & metabolic diseases reflecting human disease pathology and progression; focus on the cardiometabolic aspects of CKD with potential integration into pre-clinical models of MASH, Cirrhosis, or Obesity
• Oversee experimental design and results of junior scientists; assume additional responsibilities including mentoring and developing scientific staff
• Communicate scientific results orally and in writing at internal and external meetings, leadership discussions, and global alignment meetings
• Stay current with relevant scientific literature and maintain visibility outside the functional area
• Maintain compliance with regulatory SOPs and IACUC procedures with high level of scientific and data integrity
• Substantial hands-on benchwork is expected
• This position requires moderate physical activity to complete work in the vivarium and laboratory. This includes but is not limited to standing for extended durations (>2 hours), working under a biosafety hood/cabinet for extended durations (>2 hours), bending, lifting (up to 20 lbs), squatting, pushing/pulling, and reaching. This is in addition to handling and restraint of small laboratory animals (rats, mice; >50 at a time) daily and often within a specified timeframe
• This position required use of personal protective equipment (PPE) including respiratory, eye, hand, and foot protection
  
  
  

Requirements

• Ph.D. Degree in Cardiovascular Disease, Pharmacology, Physiology, or equivalent experience in a related field
• Proven track record performing rodent cardiovascular techniques, including echocardiography
• Proven ability to develop, execute, and troubleshoot in vivo pharmacology models
• Ability to problem-solve with scientific curiosity
• Effective communicator (oral & written) and team player
• Willingness to support weekend in vivo work as needed
• Advanced skillset for in vivo techniques including detailed theoretical and hands-on experience using advanced small animal echocardiography and ability to integrate PK/TE/PD concepts
• Proven track record to develop and execute in vivo pharmacology models, with emphasis in renal and/or cardiovascular disease research
• Demonstrated ability to train, mentor, and collaborate with junior scientists effectively in a matrixed and culturally diverse environment
• Ability to work in a fast-paced collaborative environment while maintaining a high level of attention to detail
• Ability to prioritize efforts and multi-task to deliver on overlapping commitments
• Effective communication, both orally and in writing, within an interdisciplinary environment
• History of high-quality peer-reviewed publications, abstracts, and/or presentations at scientific conferences
  
  
  

Compensation:

 This position, Senior Scientist , offers a base salary typically between $140,000.00 and $222,000.00.  The position may be eligible for a role specific variable or performance based bonus and or other compensation elements. For an overview of our benefits please click here.

Eligibility Requirements:

• Must be legally authorized to work in the United States without restriction
• Must be willing to take a drug test and post-offer physical (if required)
• Must be 18 years of age or older
  
  
  

Our Company

Why Boehringer Ingelheim?

With us, you can develop your own path in a company with a culture that knows our differences are our strengths - and break new ground in the drive to make millions of lives better.

Here, your development is our priority. Supporting you to build a career as part of a workplace that is independent, authentic and bold, while tackling challenging work in a respectful and friendly environment where everyone is valued and welcomed.

Alongside, you have access to programs and groups that ensure your health and wellbeing are looked after - as we make major investments to drive global accessibility to healthcare. By being part of a team that is constantly innovating, you'll be helping to transform lives for generations.

Want to learn more? Visit https://www.boehringer-ingelheim.com