Demo

Senior Engineer, Applied AI & Engineering Platforms

BioSpace
North Chicago, IL Full Time
POSTED ON 6/19/2026
AVAILABLE BEFORE 7/17/2026
Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

Job Description

Join an inclusive, collaborative Business Technology Solutions (BTS) team as a Sr Engineer, Applied AI & Engineering Platforms at AbbVie. This is a hands-on, lead technical engineering role at the center of AbbVies generative and agentic AI transformation building intelligent, autonomous systems and scalable agentic workflows that will accelerate drug discovery, streamline clinical and regulatory operations, and reimagine how AbbVie works across every function.

You will design and own the AI foundations layer that underpins all agentic capabilities across the enterprise, establish engineering standards that make AI systems reliable and auditable inGxP-regulated environments, and serve as a technical authority guiding platform teams, data scientists, and application engineers across the organization.

This is not a research or prototyping role. You will architect, build, and operate production-grade multi-agent systems used in clinical, commercial, and operational domains working alongside enterprise architecture, platform security, data engineering,MLOps, and domain subject matter experts to ensure every system is deployable, governed, and compliant from day one.

Responsibilities

Agentic System Design & Engineering

  • Architect and own production-grade multi-agent systems using orchestration frameworks (LangChain,LangGraph,CrewAI, OpenAI Agents SDK,AutoGen/AG2, Semantic Kernel), making deliberate decisions on state management, routing, memory architecture, and failure handling.
  • Design agent cognitive architectures planning loops (ReAct,Reflexion,CoT), tool-use patterns, memory systems (short-term, episodic, semantic), and self-evaluation loops.
  • Build multi-agent coordination patterns (supervisorworker, peer collaboration, A2A protocols) aligned with emerging open standards including MCP server integration to connect agents to enterprise systems, clinical data platforms, and regulatory repositories.


AI Foundations Layer

  • Design andmaintainshared AI infrastructure: LLM gateway/routing, embedding services, vector stores, RAG pipelines, prompt management, and model evaluation harnesses across all agentic products.
  • Establish model selection and governance spanning hosted providers (Claude, GPT, Gemini) and self-hosted models, including fine-tuning pipelines (LoRA/QLoRA) for pharmaceutical-specific tasks.
  • Build context engineering standards managing context windows, retrieval strategies, chunking, re-ranking, hybrid search, and query routing for enterprise-scale clinical and scientific knowledge with guardrails, safety layers, content filters, and HITL escalationappropriate forGxPenvironments.


Agentic Engineering SDLC

  • Define the end-to-end SDLC for agentic systems from design through evaluation, deployment, and continuous monitoring treating agent behavior as a first-class software artifact subject to change control.
  • Build agent evaluation frameworks (golden test sets, LLM-as-judge scoring, regression detection, task-completion benchmarks, latency/cost dashboards) and CI/CD pipelines with automated evaluation gates, drift detection, and rollback capabilities.
  • Establish traceability, audit logging, and versioning standards supportingGxPvalidation, 21 CFR Part 11, and AbbVies AI governance policy.


Observability, Reliability & AIOps

  • Implement full-stack observability (LangSmith,Langfuse,OpenTelemetry): trace-level logging, token/cost tracking, latency profiling, and anomaly detection on agent behavior.
  • Own production reliability retry logic, fallback strategies, circuit breakers, graceful degradation, and HITL escalation for regulated workflows.Monitor forbehavior drift and decision inconsistency; implement continuous feedback loops without introducing regressions.
  • Integrate agentic services with enterprise platforms (Salesforce, MuleSoft, Veeva, SAP, Databricks, ServiceNow) using MCP and standardized API patterns.


Governance, Compliance & Responsible AI

  • Design agent authorization models operationalizing AbbVies AI risk tiers (HIGH/LOW), defining what agents can access, act on, and decide autonomously versus what requires human approval.
  • Implement governance controls aligned with FDA AI/ML guidance, ICH E6/E8, EU AI Act, and AbbVie internal policy ensuring compliance with data residency, privacy (HIPAA, GDPR), least-privilege access, prompt injection defense, and secure MCP/A2A integrations.
  • Build validation artifacts satisfying audit requirements for agents in clinical, regulatory, andGxP-controlled workflows.


Cross-Functional Technical Leadership

  • Partner with product managers, data scientists, enterprise architects, platform security, and domain teams to translate pharmaceutical problems into agent system designs; define reusable patterns and shared platform components that accelerate development across teams.
  • Mentor engineers on the agentic AI platform, conduct architecture reviews,establishengineering standards, and foster a culture of production-quality AI development while driving adoption of emerging standards (MCP, A2A, evaluation benchmarks) relevant to AbbVies environment.


Qualifications

Required:

  • Minimum years of experience: 6 with Bachelors, or 5 with Masters, or0 with PhD in software engineering with demonstrated depth in AI/ML systems, NLP/LLM applications, or production AI platforms including experiencebuilding Generative AI or LLM-powered applications in production environments.
  • Demonstrated hands-on experience architecting and deploying production-grade AI agent or multi-agent systems not prototypes or POCs using at least one major orchestration framework (LangChain,LangGraph,CrewAI, OpenAI Agents SDK,AutoGen/AG2, or Microsoft Semantic Kernel).
  • Strong Pythonproficiencyincluding async programming (asyncio), RESTful API design (FastAPI), system design patterns for scalable distributed AI systems, and production-quality coding practices.
  • Hands-on experience building and operating RAG pipelines: embedding models, vector databases (e.g.,pgvector, Pinecone, Azure AI Search), chunking strategies, hybrid retrieval, and retrieval evaluation. Familiarity withLlamaIndexor similar RAG frameworks is a plus.
  • Experience with one or more cloud AI platforms (AWS Bedrock, Azure AI Foundry, or Google Vertex AI) including serverless inference and managed agent services.
  • Solid understanding of prompt engineering at the system level: system prompt design, structured output formats, tool-call schemas, context engineering, and prompt versioning.
  • Clear communication skills ability to articulate agent architecture decisions, risk tradeoffs, and compliance implications to both technical engineers and non-technical business stakeholders.


Preferred

  • WorkingproficiencywithLLMOps/AIOps tooling (LangSmith,Langfuse,MLflow, or equivalent) for agent observability, experiment tracking, and production monitoring.
  • Experience designing and implementing agent evaluation frameworks including test dataset design, LLM-as-judge scoring, regression benchmarking, and responsible AI practices.
  • Open-source contributions, published work, or conference presentations in agentic AI, multi-agent systems, LLM engineering, machine learning, or related areas.
  • Strong experience with MCP (Model Context Protocol), A2A (Agent-to-Agent), or equivalent tool-integration and agent communication standards; TypeScript or Goproficiencyfor MCP server development or full-stack AI delivery.
  • Experience in pharmaceutical, life sciences, biotech, or other regulated industry environments with exposure toGxP, 21 CFR Part 11, FDA AI/ML guidance, ICH E6/E8, or ISO 42001 standards.
  • Hands-on experience integrating AI agents with enterprise platforms (Salesforce, Veeva Vault, SAP, ServiceNow, Databricks, MuleSoft) or processing multimodal clinical/scientific data.
  • Background in distributed systems or microservices architecture (event-driven, serverless, Kubernetes); familiarity with Docker, container orchestration,PyTorch, or Hugging Face for model experimentation.
  • AWS, Azure, or GCP professional-level certifications; familiarity with AI-assisted development workflows (Cursor AI, GitHub Copilot).


Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

  • The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographiclocation,andwemay ultimately pay more or less than the posted range. This range may bemodified in thefuture.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
  • This job is eligible toparticipate in our short-term incentiveprograms.


Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremains in the Company'ssoleandabsolutediscretion unless and until paid andmay bemodified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

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