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Principal Scientist - Cancer Vaccines

BioSpace
Englewood, NJ Full Time
POSTED ON 11/4/2026
AVAILABLE BEFORE 12/3/2026
ICR's Cancer Prevention science centers on developing preventive cancer vaccines. We are hiring a Principal Scientist with a deep background in peptide-based vaccine development, cancer immunology and immuno-oncology. As part of our mission to prevent age-related disease, training human immune systems to spot and destroy cancer before it becomes a problem is critical. We truly believe that an ounce of prevention is worth a pound of cure.

With Us, You'll Get To

Lead ICR's Cancer Prevention Group in researching and developing novel preventive cancer vaccines

Drive end-to-end design, execution and interpretation of preclinical vaccine studies, directly shaping the path to human translation

Collaborate closely external KOLs and CRO partners to turn cutting-edge cancer immunology insights into first-in-class preventive vaccine programs

Please Apply If You Have

A PhD, MD or both and at least 10 years of vaccine development experience, preferably cancer vaccines

In-depth knowledge of and experience researching personalized cancer vaccines, including peptide-based vaccines and neoantigen-based cancer vaccines

Extensive experience with vaccine epitope identification, selection/prioritization (of neoantigens), vaccine adjuvants and immune response monitoring

Experience with molecular T cell receptor repertoire analysis and tracking, T cell proliferation assays, cytokine release assays and ELISPOT

Experience deriving antigen-specific T cell clones and lines

Expertise in cancer stem cell antigens, tumor-associated antigens, neoantigens, immuno-editing and immuno-monitoring

Extensive knowledge of and experience with vaccine delivery systems, including peptide-, cell- and viral-based systems

The ability to work well with CROs and manage external projects

Even if you don't meet all of these criteria, please apply anyway

And You'll Need

The ability to work in the United States without sponsorship

To have an easygoing, hard-working personality

Salary

Starting base pay range: $165,000/yr - $215,000/yr

Starting additional compensation range: $7,500/yr - $20,000/yr

Salary : $7,500 - $215,000

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