Demo

Lab Manager

BioSpace
Philadelphia, PA Full Time
POSTED ON 12/24/2025
AVAILABLE BEFORE 1/22/2026
Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.

Legend Biotech is seeking a Lab Manager as part of the R& D team based in Philadelphia, PA.

Role Overview

Legend Biotech is seeking an experienced lab manager for its new state-of-the-art R&D laboratory in Philadelphia, PA. The new lab in Philadelphia will provide critical research of Legend pipeline development from early discovery to IND submission related in vivo and in vitro studies. The ideal candidate should have 8 years of experience supporting R&D lab operation, logistics, procurement and facilities. Hands-on instrument and reagent inventory management experience is required. Previous experience in the setting of cell therapy research and development is a plus. This role will interact with stakeholders mainly at the Philly site and other R&D sites in NJ. This role will help with budget planning, drive lab operation efficiency and establish the future of laboratory operation.

Key Responsibilities

  • Be responsible for lab operations to support uninterrupted R&D activities on site.
  • Oversee lab set-up, space planning and general cleanliness of the lab.
  • Initiate and act as SME for instrument and LIMS installation and qualification.
  • Set up and own service contracts with manufacturers for analytical equipment.
  • Partner with Warehouse and Logistics for consumable and material ordering, storage and distribution.
  • Actively manage and escort external vendors..
  • Facilitate cold storage management.
  • Serve as a bridge to interact with procurement, finance, IT, Engineering & facilities, Warehouse & Logistics and other functions.
  • Ensure compliance with procedures from other departments where the lab and lab activities are in scope.
  • Create and oversee equipment cleaning program.
  • Partner with Facilities to coordinate timing and lab impacts for maintenance and calibration activities.
  • Coordinate interactions with other R&D sites.
  • Usage and budget planning on lab consumables & Materials.
  • Create response plan for alarms where there is the potential for material impact.


Requirements

  • Bachelor's degree.
  • 8 years of experience managing R&D lab operation in industry or academic setting with more than 30 scientists.
  • Demonstrated ability to effectively interact with multiple key stakeholders.
  • Working experience with MS Office Suite.
  • Working experience with LIMS is a plus.
  • Excellent record keeping skills.
  • Capable of multi-tasking and great project management skills.
  • Good problem-solving skills and willingness to be accountable when facing the challenges of this new, dynamic and evolving operation.
  • Excellent verbal and written communication skills.


The anticipated base pay range is

$81,273 - $106,669 USD

Benefits

We are committed to creating a workplace where employees can thrive - both professionally and personally. To attract and retain top talent in a highly competitive industry, we offer a best-in-class benefits package that supports well-being, financial stability, and long-term career growth. Our offerings are designed to meet the diverse needs of our team members and their families, ensuring they feel valued and supported every step of the way. Highlights include medical, dental, and vision insurance as well as a 401(k)-retirement plan with company match that vest fully on day one. Equity and stock options are available to employees in eligible roles. We offer eight weeks of paid parental leave after just three months of employment, and a paid time off policy that includes vacation days, personal days, sick time, 11 company holidays, and 3 floating holidays. Additional benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs - demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work. Please note: These benefits are offered exclusively to permanent employees. Contract employees are not eligible for benefits through Legend Biotech.

EEO Statement

It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.

Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. Legend may adjust base salary or other discretionary compensation at any time based on individual, team, performance, or market conditions.

Legend Biotech maintains a drug-free workplace.

Salary : $81,273 - $106,669

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