Director, US Marketing Operations

Company Overview

Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.

Role Summary

The Director, US Marketing Operations establishes and leads the tactical execution of marketing operations, with an immediate focus on launch readiness for Dyne’s lead assets in Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1). As Dyne transitions into a fully integrated biotechnology company, this role plays a critical part in building the systems, processes, and operational infrastructure required to enable compliant, impactful, and efficient delivery of therapeutic education to US external stakeholders.

The Director serves as a key partner across Marketing, Commercial Operations, Medical Affairs, Market Access, Patient Services, Regulatory, Legal, Compliance, and Information Technology, driving operational excellence and enabling speed to market in highly regulated and complex therapeutic landscapes

Primary Responsibilities

Commercial MLR Review Committee Leadership

• Owns US Marketing Operations as a capability, setting standards, governance, and scalable operating models across the Commercial organization.
• Chair and lead the Dyne Commercial Medical, Legal, and Regulatory review committee and manage the end-to-end content review and approval process for Commercial-led therapeutic education
• Partner closely with Marketing, Medical, Legal, and Regulatory teams to foster a collaborative, solution-oriented review culture
• Ensure timely, compliant review of HCP, payer, and patient-facing materials and optimize systems supporting content workflows such as Veeva Vault PromoMats
• Partner and collaborate with Regulatory, Legal, and Compliance to maintain policies, procedures, and governance aligned with evolving regulatory standards
  
  
  

HCP and Consumer Engagement

• Design, develop, and implement a fit-for-purpose HCP and consumer peer-to-peer engagement model that meets the unique educational needs of rare disease launches in DMD and DM1
• Oversee HCP and consumer engagement operations across the Commercial organization, including nomination, contracting, onboarding, training, logistics, and relationship management
• Ensure compliance with all applicable industry regulations and internal policies, including fair market value requirements and Sunshine reporting
  
  
  

Marketing Excellence and Performance

• Serve as a strategic partner to Dyne Brand Teams, aligning Marketing Operations capabilities to commercial objectives to enhance executional effectiveness
• Drive continuous improvement across marketing operations processes to support agility, scalability, and compliance
• Oversee print fulfillment operations and manage promotional asset lifecycle planning
• Partner with Commercial Operations, Information Technology, and Analytics teams to enable systems that track performance and integrate insights into campaign design and optimization
• Ensure personalized and precise customer engagement through effective use of data, segmentation, and targeting strategies
  
  
  

Congress and Meeting Management

• Lead planning and drive the execution of US HCP and consumer-facing congresses, conventions, and field-sponsored events to maximize Dyne’s presence and engagement impact
• Partner closely with Marketing, field-facing teams, and Medical Affairs to coordinate KOL engagement strategies at congresses, ensuring operational excellence, brand alignment, and compliance
  
  
  

Qualifications

• Bachelor’s degree required; advanced degree such as MBA or MPH preferred
• 10 years of experience in the pharmaceutical or biotechnology industry, with experience supporting rare disease or accelerated approval launches preferred
• Experience leading promotional review processes in regulated environments
• Demonstrated ability to thrive in fast-paced environments with strong prioritization and problem-solving skills
• Proactive, adaptable, and solution oriented, with a track record of delivering results under tight timelines
• Deep understanding of US regulatory requirements and compliance standards governing promotional activity
• Excellent communication, interpersonal, and stakeholder management skills
• Strong business acumen with the ability to translate strategic objectives into operating execution
• Experience with commercial systems and platforms such as Veeva Vault PromoMats highly preferred
• Experience operating effectively in a small, rapidly growing biotech environment with comfort navigating ambiguity
  
  
  

MA Pay Range

$188,000 - $240,000 USD

The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.

The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.

Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.