Director – Medical Affairs- Cardiometabolic Health (CMH)- US

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Role Overview

We are seeking an experienced medical affairs leader to serve as Executive Director within U.S. Cardiometabolic Health (CMH). This role is intended for a senior Medical Affairs scientific leader with deep expertise across clinical science, evidence generation, scientific exchange, and U.S. medical strategy.

The Executive Director provides strategic medical and scientific leadership across key U.S. Medical Affairs activities and is accountable for leading teams delivering the full scope of Medical Affairs responsibilities. These include medical strategy execution, evidence generation, scientific communications, external engagement, medical education, and compliant governance, including leadership of Medical/Legal/Regulatory (MLR) review.

Position Summary

The Executive Director, Cardiometabolic Health (CMH), U.S. is responsible for shaping and executing the U.S. Medical Affairs strategy across priority CMH brands and indications. Serving as a senior scientific and strategic partner to the U.S. business and global Medical Affairs colleagues, this role translates complex scientific and clinical data into actionable insights that inform evidence generation, external scientific exchange, and patient focused strategies.

This role requires strong cross functional leadership and influence, with accountability for end-to-end Medical Affairs planning, execution, and impact. The Executive Director provides direct and/or matrix leadership to Medical Affairs contributors and serves as a senior scientific leader within Medical Affairs governance forums, including oversight and leadership of scientific and medical content through the MLR process.

Key Responsibilities

Medical Strategy & Scientific Leadership

• Shape and lead execution of the U.S. Medical Affairs strategy for CMH, aligned to scientific evidence, unmet medical needs, and patient outcomes.
• Serve as a senior scientific subject matter expert across CMH therapeutic areas, with accountability for scientific quality and integrity across U.S. medical initiatives.
• Translate emerging clinical and scientific data into insights that inform medical strategy, evidence planning, and external engagement.
  
  
  

Evidence Generation & Scientific Enablement

• Provide senior scientific leadership for evidence generation activities, including clinical endpoints, real-world evidence (RWE), health outcomes, and patient reported outcomes.
• Partner cross functionally to ensure alignment between U.S. evidence plans and global medical strategy.
• Guide scientific publications, congress strategy, and scientific communications in accordance with Medical Affairs standards.
  
  
  

People Leadership & Medical Affairs Oversight

• Provide direct and/or matrix leadership to CRSs, CRPs, and other Medical Affairs contributors across the U.S. CMH portfolio.
• Lead teams across the full spectrum of Medical Affairs responsibilities, including strategy, scientific exchange, evidence execution, publications, medical education, and governance.
• Set clear expectations, prioritize work, and ensure timely delivery of high-quality, compliant scientific outputs.
• Maintain end-to-end accountability for Medical Affairs initiatives from strategy through execution and impact assessment.
• Coach, develop, and mentor scientific talent; support succession planning and capability building.
• Foster an inclusive, high performing culture grounded in scientific excellence, collaboration, and integrity.
  
  
  

Governance & Compliance

• Serve as a senior scientific leader within Medical Affairs governance and decision-making forums.
• Provide oversight and leadership for U.S. medical content and strategy through the MLR review process, ensuring compliance with internal and external standards.
  
  
  

Basic Qualifications

• An advanced health/medical/scientific (for example, in Pharmacology, physiology, microbiology) or related graduate degree such as MD, DVM, PharmD, PhD, MSN with advanced clinical specialty (Clinical Nurse Specialist/Nurse Practitioner) with 10 years years of clinical experience or pharmaceutical experience (preferably in Medical Affairs)
• OR
• Have a BS or master's degree in health/medical/scientific or related field and 15 years of pharmaceutical experience that is directly related to at least one of the following: clinical trial experience in areas relevant to drug discovery, development or direct role and contribution to medical content.
  
  
  

Additional Preferences

• Significant experience in Medical Affairs, clinical research, pharmaceutical development, or related scientific roles.
• Demonstrated leadership of scientific, clinical, or medical professionals in complex, matrixed environments.
• Strong understanding of cardiometabolic disease, with the ability to interpret and apply clinical and real world data to inform strategy.
• Proven ability to influence cross functionally and operate as a trusted scientific partner to senior stakeholders.
  
  
  

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$177,000 - $308,000

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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