Biomarker and Precision Medicine Lead

Job Title: Biomarker and Precision Medicine Lead

Location: Cambridge, MA

About The Job

Join the engine of Sanofis mission where deep immunoscience meets bold, AI-powered research. In R&D, youll drive breakthroughs that could turn the impossible into possible for millions.

Sanofi's Biomarkers & Precision Medicine group, within the Translational Medicine Unit, seeks an experienced Biomarker and Precision Medicine Lead. This data-driven position focuses on leading the development and implementation of decision enabling translational medicine strategies for our robust pipeline in Immunology and Inflammation with a specific focus on our growing pipeline in Inflammatory Bowel Disease (IBD). The role is critical in identifying and validating biomarkers that predict patient response, demonstrate molecular activity including target engagement, and correlate with clinical outcomes, as well as leading forward and reverse translational research activities in IBD.

About Sanofi

Were an R&D-driven, AI-powered biopharma company committed to improving peoples lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve peoples lives.

Main Responsibilities

Scientific Leadership & Strategy:

• Develop comprehensive and decision enabling biomarker and precision medicine strategies for research and development (Ph1-Ph4) projects
• Design approaches for implementing biomarkers in clinical studies using various platforms (omics, bioimaging, etc.)
• Provide scientific expertise in translating biological pathways to clinical markers and clinical markers into biological pathways
• Review and interpret complex clinical and non-clinical biomarker data sets
• Identify and validate novel biomarkers for patient selection and monitoring
  
  
  

Project Management & Execution

• Lead cross-functional translational medicine sub-teams and lead and coordinate the biomarker identification, assay development, implementation and execution efforts in a highly matrixed environment
• Ensure timely execution of biomarker studies within budget constraints
• Evaluate and select optimal platforms and methodologies for biomarker data generation
• Monitor study progress and troubleshoot technical challenges
• Maintain project documentation and regulatory compliance
• Author biomarker portions of clinical documents, including clinical protocols and reports, Investigator Brochures etc.
  
  
  

Collaboration & Communication

• Work closely with global multidisciplinary teams including research scientists, clinical pharmacologists, clinicians, clinical and biomarker operations, regulatory and data scientists
• Engage with external key opinion leaders and research partners
• Initiate and lead external collaborations
• Present strategies and results at internal and external meetings
• Contribute to regulatory documents and scientific publications
• Support business development activities related to biomarker strategies
  
  
  

About You

Required Qualifications:

• MD, MD/PhD, or PhD with 5 years of industry experience in biomarker/ translational or clinical research in a global highly matrixed environment
• Demonstrated expertise in immunology and inflammation indications
• Strong understanding of biomarker development and implementation in global clinical trials for drug development
• Strong understanding of drug development and clinical trial design
• Experience with various biomarker platforms and technologies
• Proven track record in translational research
• Excellence in written and verbal communication
• Demonstrated experience in leading teams in a highly matrixed environment
  
  
  

Preferred Qualifications

• Experience in Gastrointestinal diseases, preferably in IBD; additional experience in Transplantation is a plus
• Experience with bioinformatics and computational methods
• Knowledge of biomarker assay development for clinical use
• Publication record in Immunology and IBD
• Experience in regulatory interactions
• Project management certification
  
  
  

Experience/Education

• Bachelors degree plus minimum 15 years of relevant experience in an academic or biopharmaceutical setting OR Masters Degree plus minimum 12 years post MS degree relevant experience in an academic or biopharmaceutical setting OR Ph.D. plus a minimum of 10 years post PhD relevant experience in an academic or biopharmaceutical setting.
  
  
  

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether its through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks gender-neutral parental leave.
  
  
  

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.