What are the responsibilities and job description for the Scientist II position at BioPhase?
Scientist II – Analytical Development (Biologics)
Status: Contract to hire
Compensation: $64/hr - $73/hr DOE
Overview
A growing biotech organization is looking for a driven Scientist II to support analytical development activities for next-generation biologic therapeutics. This position is based in the San Diego area and plays a key role in method development, characterization, and early CMC support for complex protein and antibody formats.
The role is ideal for someone who enjoys hands-on bench work, problem-solving across multiple analytical platforms, and collaborating with cross-functional teams advancing early-stage biologics.
Primary Responsibilities
- Develop, refine, and implement analytical methods for characterization, release, and stability of diverse biologic molecules (e.g., antibodies, bispecifics, conjugates).
- Perform routine and non-routine analyses using platforms such as HPLC (SEC, HIC, IEX), capillary electrophoresis (icIEF, CE-SDS), UV-Vis, pH/osmolality measurements, and impurity assessments (e.g., HCP).
- Interpret complex data sets, identify trends, and deliver insights that guide research and process development decisions.
- Maintain high-quality documentation in electronic lab notebooks and prepare technical documents including study protocols, reports, and method descriptions.
- Recommend improvements to analytical workflows and stay current with emerging technologies in separation sciences and biologics analysis.
- Serve as the analytical representative on internal project teams spanning Discovery, Process Development, and CMC.
- Support external activities such as method transfer, analytical lifecycle management, and stability program oversight.
Qualifications
- Advanced degree in analytical chemistry, biochemistry, or a related field, with ~3 years of relevant industry experience in biologics analytical development (or an equivalent combination of education and experience).
- Deep expertise in separation science and demonstrated capability in method development and qualification/validation.
- Strong practical experience operating modern analytical instrumentation for biotherapeutic characterization.
- Solid understanding of protein structure, degradation pathways, and common challenges in biologic development.
- Comfortable working in a small, fast-moving environment and willing to both learn from and mentor others.
- Excellent technical writing skills and familiarity with drafting content for regulatory submissions.
- Knowledge of early-stage development principles, manufacturing science/technology, unit operations, and GxP concepts.
- Experience supporting formulation, process development, or drug product teams is a plus.
Salary : $64 - $73