Research Associate II

Summary

Bionano is seeking a Research Associate II to generate DNA samples by extracting ultra-long DNA from cells, label using Bionano’s DLS (Direct Label and Stain) protocol, and run the samples on Binano systems to support continuous improvement. The position will involve optimizing electrophoresis DNA loading conditions within Bionano’s nano-channel array, evaluating performance, building/testing prototype chips, developing new methods and materials for chip assembly, and designing accelerated stability studies. 

Primary Duties and Responsibilities

• Perform experiments to assess and improve DNA throughput on the Stratys Chip(30%).
• Track experiments, analyze results, and present data to be reviewed by Bionano Team(20%).
• Build prototype nano-channel Chips. (20%)
• Generate DNA samples to be used in chip studies.(10%).
• Work with supervisor and operations to identify parameters to drive continuous process improvement(10%).
• Provide feedback to improve software and hardware system performance(5%).
• Other duties as assigned(5%).

Required Skills and Abilities

• At least 1 year of experience with fluorescent microscopy, pipetting, electrophoresis, and standard wet bio lab bench procedures.
• Ability to analyze data from multiply sources and use analysis tools such as (but not limited to) python, Jmp, excel, or R to aide in analysis.
• Working knowledge of DNA extraction and labeling methods.
• Basic understanding of genomics and human genetics.
• At least 1 year of experience with NGS and/or long-read sequencing technologies.
• Proven success working within a cross-functional team.
• Detail oriented with strong troubleshooting, communication, and documentation skills.

• Ability to ask questions, take initiative, and work in a fast-paced team environment.

Education, Certifications, Licenses

• Bachelor’s degree in bio-engineering, biophysics, physics, chemistry, or biotechnology is required. Master’s degree preferred.
• Minimum of 3 years of direct experience in research and development in the genomics industry required.

Additional Requirements 

• Work Location: Onsite – San Diego, CA
• Travel Requirements:

• Minimal travel time expected(less than5%)

• Physical Requirements and Work Environment:

• Sit and stand for prolonged periods 
• Repeating motions that may include the hands, wrists and/or fingers 
• Use of hands to finger, handle, or feel, and reach with hands and arms
• Stand and/or move about the office or in various environments (including tight and confined spaces), or from one worksite to another
• Specific visual abilities, including close vision and ability to adjust focus, read, review, and assess the accuracy and thoroughness of the work assigned
• Verbal abilities require communicating with others to exchange information
• Occasionally adjusting or moving objects up to 40 pounds in all directions
• Work environment involving low/high temperatures; hazardous conditions, low ventilation, noisy environments, small/enclosed spaces

• In-person interaction with others indoors and outdoors
• Use standard computer, telephone and related equipment for communication,andrecordkeeping

The above physical requirements and work environment characteristics generally reflect those of this position but is not an exhaustive list. Reasonable accommodations may be made to enable individuals with qualified disabilities to perform the essential functions of the position, provided that such accommodation does not impose an undue hardship on the Company.

Disclaimer

Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time. This description generally reflects management’s assignment of essential functions but is not intended to be a comprehensive list of the duties and responsibilities of the position, and it does not limit or restrict the duties and responsibilities that may be assigned from time to time. The duties, responsibilities and job description of this role are subject to change at any time without notice.