What are the responsibilities and job description for the Principal Investigator position at Bend Bioscience?
At Bend Bioscience, our Core Values Shape Everything We Do:
How You Will Make An Impact
- AUTHENTIC – Be vulnerable, build trust
- CURIOUS – Ask questions, be adaptable, speak up
- ACCOUNTABLE – Own it, meet commitments, communicate transparently
- COLLABORATIVE – Engage others, stay open-minded
- FLEXIBLE – Listen actively, be thoughtful, make informed decisions
- CARE – Be passionate, act with integrity
- BLAZE TRAILS – Push boundaries, challenge constraints
- EXCELLENCE – Learn, improve, create value
- FOCUS – Pay attention to details, stay determined, deliver exceptional service
How You Will Make An Impact
- Lead internal project teams and consult site subject matter experts (SMEs) to solve unique and complex problems that have a broad impact on the business and enable progression of challenging compounds.
- Manage multi-disciplinary project team of scientists to develop technical capabilities and know how, progress product development projects, and support individual development and career growth.
- Work with clients and internal SMEs to define problem statements, conduct technology selection, and outline technical program strategies based on target product profile.
- Ensure analytical method development and material science considerations for formulations are sound and phase appropriate.
- Lead programs and project teams to ensure quality of technical approach, progress reports, and successful client relationships.
- Understand, review, and optimize workplans to effectively challenge formulation attributes critical to successful formulation strategies.
- Be a subject matter expert in at least one pharmaceutical drug product development technical focus area and staying aware and current with pharmaceutical industry formulation and process advancements.
- Present technical results and recommendations to the client. Serving as the primary technical point of contact for client programs (internally and externally).
- Utilize risk assessments to effectively communicate and plan for program considerations associated with formulations and processes.
- Support GMP manufacturing by participating in activities, including, development study design and execution, training, clinical tech transfer, investigation support, equipment design and qualification, and change control.
- Identify and propose new technical opportunities while working on client programs.
- Mentor colleagues and team members on technical aspects of successful formulation and process development through program progression and support as an SME.
- PhD, MS, or BS in chemistry, chemical engineering, or related field with minimum 5 years of experience in pharmaceutical industry with a focus on chemistry, manufacturing, and controls.
- Experience and understanding of drug product formulation and processing fundamentals, including experience with scale-up and support for GMP manufacturing.
- Experience and understanding of spray dried dispersion formulation and processing fundamentals, including experience with scale-up and support for GMP manufacturing.