What are the responsibilities and job description for the Director, Real-World Evidence (RWE) Scientist — Oncology position at Barrington James?
About The Role
We're looking for a true epidemiologist with deep RWE expertise who can move fluidly between strategy and hands-on execution, leading evidence generation for rare tumour assets end to end, from designing non-interventional studies (NIS) through to regulatory-facing evidence packages. This is not a pure strategy role, and it's not a pure execution role: you'll need to want, and be capable of, both.
What You'll Do
Lead RWE strategy and end-to-end execution for rare tumour assets
Design and scope non-interventional studies (NIS), including defining the right endpoints and evidence questions
Own external control arm strategy and evidence generation
Source, evaluate and select vendors to support studies
Lead regulatory-facing interactions and evidence generation — this role interfaces with regulatory and clinical development, not payers
Present project strategy directly to the project strategy team and to global product team leaders and product heads
Translate complex, methodological RWE concepts into clear, digestible input for cross-functional stakeholders
Collaborate closely with adjacent quantitative functions — clinical measurable sciences, data science, and the broader patient-focused evidence team — in a highly collaborative, flat-structured environment
What You'll Bring
A genuine epidemiology background with strong real-world evidence (RWE) expertise
Experience in non-interventional study (NIS) design, external control arms, evidence generation, and regulatory science
Oncology or rare disease experience is essential
A demonstrated ability — and desire — to operate across both strategic and hands-on/execution work; candidates seeking a purely strategic remit, or who are only comfortable executing without strategic input, won't be the right fit
Strong communication skills, with the ability to simplify methodologically dense material for varied audiences
Comfort working directly with senior product and clinical development stakeholders