Demo

Biopharmaceutical Manufacturing Associate (Upstream/Downstream)

Astrix
Chicago, IL Full Time
POSTED ON 3/25/2026
AVAILABLE BEFORE 8/30/2026
Pay Rate Low: 25 | Pay Rate High: 35

Biopharmaceutical Manufacturing Associate (Upstream/Downstream)

Location: Chicago, IL (On-site)

Schedule: 3rd Shift: 10:00pm–6:30am

Employment Type: 5 month Contract-to-Hire

Overview

Our client, a growing biopharmaceutical manufacturing organization, is seeking Manufacturing Associates to support production of biologic products in a cGMP-regulated environment. This is an excellent opportunity for recent graduates (Bachelor’s or Master’s level) or early-career professionals looking to gain hands-on experience in biotech manufacturing operations.

Key Responsibilities

  • Perform upstream and/or downstream bioprocessing activities in a pilot plant or full-scale manufacturing environment
  • Support cell culture, fermentation, and harvest processes using bioreactors (up to 250L scale)
  • Execute purification processes including column chromatography and filtration (TFF, depth filtration, etc.)
  • Prepare media, buffers, and solutions following batch records and SOPs
  • Perform aseptic processing and fill/finish operations in cleanroom environments
  • Monitor processes using PLC/HMI systems and perform in-process testing (pH, conductivity, etc.)
  • Accurately complete batch records and cGMP documentation
  • Assist with deviations, CAPA, and change control documentation as needed
  • Troubleshoot equipment and support continuous improvement initiatives
  • Maintain cleanroom standards, safety compliance, and proper material handling procedures

Qualifications

  • Bachelor’s or Master’s degree in Biology, Biotechnology, Biochemistry, Chemistry, or related field preferred
  • 1–5 years of experience in biotech or pharmaceutical manufacturing (internships/co-ops highly considered)
  • Hands-on experience with cell culture and/or purification (chromatography, filtration) required

(Note: Academic-only bench research without scale-up/manufacturing exposure is not sufficient)

  • Exposure to cGMP environments and cleanroom operations preferred
  • Strong attention to detail with the ability to follow SOPs and batch records
  • Ability to work off-shifts (split or overnight)

Why Apply?

  • Strong opportunity for recent grads to break into biopharma manufacturing
  • Hands-on experience with real production-scale equipment and processes
  • Exposure to both upstream and downstream operations
  • Opportunity to convert to a long-term, stable position

INDBH

Salary.com Estimation for Biopharmaceutical Manufacturing Associate (Upstream/Downstream) in Chicago, IL
$55,379 to $71,404
If your compensation planning software is too rigid to deploy winning incentive strategies, it’s time to find an adaptable solution. Compensation Planning
Enhance your organization's compensation strategy with salary data sets that HR and team managers can use to pay your staff right. Surveys & Data Sets

What is the career path for a Biopharmaceutical Manufacturing Associate (Upstream/Downstream)?

Sign up to receive alerts about other jobs on the Biopharmaceutical Manufacturing Associate (Upstream/Downstream) career path by checking the boxes next to the positions that interest you.
Income Estimation: 
$42,166 - $52,471
Income Estimation: 
$60,907 - $81,557
Income Estimation: 
$59,813 - $83,853
Income Estimation: 
$70,600 - $83,423
Income Estimation: 
$72,432 - $98,680
Employees: Get a Salary Increase
View Core, Job Family, and Industry Job Skills and Competency Data for more than 15,000 Job Titles Skills Library

Job openings at Astrix

  • Astrix Wilmington, OH
  • Join a Leading Biopharma Company! We’re looking to hire a talented QC Analyst to help develop innovative treatments for chronic diseases. Apply today—this ... more
  • 1 Day Ago

  • Astrix Ridgefield, CT
  • Our client is a global, research-driven pharmaceutical manufacturer focusing on treatment options for diseases and conditions for which there is no satisfa... more
  • 2 Days Ago

  • Astrix Chicago, IL
  • Pay Rate Low: 25.00 | Pay Rate High: 30.00 Pay Rate Low: 25.00 | Pay Rate High: 30.00 Our client is one of the largest global suppliers of antiseptic produ... more
  • 2 Days Ago

  • Astrix Fort Lauderdale, FL
  • Pay Rate Low: 33 | Pay Rate High: 49 Pay Rate Low: 33 | Pay Rate High: 49 A non-profit organization that specializes in blood donation for hospitals is see... more
  • 2 Days Ago


Not the job you're looking for? Here are some other Biopharmaceutical Manufacturing Associate (Upstream/Downstream) jobs in the Chicago, IL area that may be a better fit.

  • Lensa Chicago, IL
  • Lensa is a career site that helps job seekers find great jobs in the US. We are not a staffing firm or agency. Lensa does not hire directly for these jobs,... more
  • 6 Days Ago

  • CASCO Manufacturing Bolingbrook, IL
  • Casco Manufacturing is a manufacturer of custom cable assemblies located in Bolingbrook, Illinois. We offer our customers a domestic partner to work with f... more
  • 1 Month Ago

AI Assistant is available now!

Feel free to start your new journey!