Associate Scientist, Process Development

AstraZeneca is seeking a highly motivated researcher to join the Process Development team, as Associate Scientist, supporting and contributing to the design and execution of studies to develop and optimize clinical manufacturing processes of AstraZeneca’s portfolio of engineered T cell therapies.

As a member of the Process Development team, this role will also support technology transfer to the clinical production site. Based in Santa Monica, CA, this role reports to the Senior Scientist, Process Development.

Essential Functions And Responsibilities

• Support experimental design and execute experiments to develop and optimize manufacturing processes for genome-engineered T cell products.
• Collect and analyze experimental data and present findings in team meetings. Collaborate within the project team to interpret study results and contribute to technical discussions for subsequent study design.
• Provide support across different process development areas during high-volume activities. Prepare critical process materials including formulation of media and ribonucleic protein complexes.
• Assist with process development and tech transfer of GMP manufacturing processes to internal and external manufacturing organizations.
• Stay current with scientific advancements and emerging technologies in cell therapy process development. Help evaluate new technologies and methodologies to enhance process efficiency.
• Maintain accurate and detailed laboratory notebooks and electronic records in compliance with company policies and regulatory requirements.
• Assist in preparing technical documents, including standard operating procedures (SOPs), batch records, and development reports, as needed.
• Work effectively in a team environment to meet project timeline and objectives.
• Perform other duties as assigned. Position may require weekend work.
  
  

Required Skills

• Hands-on experience with the development of engineered TCR T cell therapies.
• Hands-on experience with genome editing tools including DNA/RNA transfection approaches.
• Familiar with process development for cell therapies, including scale-up and interpretation of T-cell functional assay results (flow-cytometry, cytotoxicity, proliferation).
• Experience with authoring manufacturing batch records.
• Strong organizational and time management skills.
• Excellent teamwork and communication skills, with the ability to work collaboratively cross-functionally.
• Proficiency with Microsoft Office, including Word, Excel, Outlook and PowerPoint.
  
  

Desired Skills

• Knowledge of cGMP manufacturing and practical experience in GMP operations.
• Experience with statistical analysis software (e.g. JMP, GraphPad Prism) for analyzing and presenting data.
• Familiar with the fundamentals of the Design of Experiments approach.
  
  

Education

• BS or MS degree in Biology, Biotechnology, Biomedical Engineering, or related field with 1 years of experience for MS or 2 years of experience with BS
  
  

The annual base pay for this position ranges from $79,336.80 - $119,005.20. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

12-Jun-2026

Closing Date

29-Jun-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.