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Research Associate - Purification

Amide Technologies
Waltham, MA Full Time
POSTED ON 12/30/2025
AVAILABLE BEFORE 1/29/2026
Amide Technologies is a Massachusetts-based biotech company focused on synthesizing peptides that are difficult to obtain through existing means, bridging the gap between traditional solid phase peptide synthesis and biological expression. By using unnatural amino acids and artificial protein backbones, our team is expanding possibilities in peptide drug design.

Research Associate

Amide is seeking an exceptional individual to join our growing team as a Research Associate. The successful candidate will be a key contributor to fulfilling customer orders by performing HPLC purification of AFPS-synthesized polyamides. Applicants should be team players able to excel in a fast-paced, collaborative environment.

Responsibilities

  • Operate RP-HPLC and LCMS instrumentation to purify/ analyze peptides and proteins (1-15 kDa, with a variety of chemical modifications such as fatty acid chains, biotinylation, fluorophores, disulfides, small molecule conjugates etc.)
  • Troubleshoot challenging technical, experimental, and instrumental issues
  • Meticulously record, analyze, and organize data
  • Prepare and maintain laboratory reagents and instruments
  • Regularly discuss progress of work

Requirements

  • BS (with industry experience), MS degree or equivalent experience in chemistry, biochemistry, or related field
  • Experience purifying synthetic peptides, proteins and/ or small molecules with HPLC
  • Ability to execute established protocols with accuracy and precision, while maintaining a proactive mindset towards process improvement
  • May have experience in LC-MS, UV-VIS, peptide synthesis
  • Excellent written and verbal communication skills
  • Enthusiasm, independence, and a willingness to learn in a fast-paced, team environment
  • Committed to working collaboratively with an interdisciplinary team

The position is full time and the Research Associate will be based at the company’s headquarters in Waltham, Massachusetts, USA. Flexibility with regard to working hours is required.

Amide Technologies offers a challenging and exciting role in one of the Northeast’s most innovative biotech companies. The company offers a competitive compensation package including salary, bonus and equity.

Amide deeply values diversity and is committed to creating an inclusive environment for all employees. We are an equal opportunity employer. We consider all qualified applicants equally for employment. We do not discriminate on the basis of race, color, national origin, ancestry, citizenship status, protected veteran status, religion, physical or mental disability, marital status, sex, sexual orientation, gender identity or expression, age, or any other basis protected by law, ordinance, or regulation.

Salary.com Estimation for Research Associate - Purification in Waltham, MA
$107,298 to $135,932
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