What are the responsibilities and job description for the Synthetics Supply Manufacturing Engineer position at Amgen?
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Synthetics Supply Manufacturing Engineer
What You Will Do
Let’s do this. Let’s change the world. In this vital role you will join our Drug Substance and Drug product facilities in Thousand Oaks as part of its GMP and non-GMP manufacturing capabilities within the Synthetic Supply function.
We are seeking a candidate experienced in chemical engineering to join our operations team which is responsible for execution of small molecule active pharmaceutical ingredient (API) production and development of clinical formulations for solid oral drug product dosage forms. The candidate will be responsible for all aspects of small molecule manufacturing to advance Amgen’s early phase synthetic pipeline.
We are all different, yet we all use our unique contributions to serve patients. The Engineer professional we seek is an individual with these qualifications.
Basic Qualifications:
Master’s degree
OR
Bachelor’s degree and 2 years of Engineering experience
OR
Associate’s degree and 6 years of Engineering experience
OR
High school diploma / GED and 8 years of Engineering experience
Preferred Qualifications:
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
careers.amgen.com
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Synthetics Supply Manufacturing Engineer
What You Will Do
Let’s do this. Let’s change the world. In this vital role you will join our Drug Substance and Drug product facilities in Thousand Oaks as part of its GMP and non-GMP manufacturing capabilities within the Synthetic Supply function.
We are seeking a candidate experienced in chemical engineering to join our operations team which is responsible for execution of small molecule active pharmaceutical ingredient (API) production and development of clinical formulations for solid oral drug product dosage forms. The candidate will be responsible for all aspects of small molecule manufacturing to advance Amgen’s early phase synthetic pipeline.
- Leading reaction step scale up in up to 100 L reactor trains under the supervision of the Lab Manager.
- Equipment maintenance and cleaning
- Qualification of equipment
- Creation of batch records for us in GLP / GMP campaigns
- Project management of manufacturing timelines
- Supporting the other operational needs of the facility
- The candidate will also collaborate in multi-disciplinary teams with process development chemists, formulation scientists, engineers, analysts, EH&S, Quality, F&E, maintenance, and other supporting functions.
We are all different, yet we all use our unique contributions to serve patients. The Engineer professional we seek is an individual with these qualifications.
Basic Qualifications:
Master’s degree
OR
Bachelor’s degree and 2 years of Engineering experience
OR
Associate’s degree and 6 years of Engineering experience
OR
High school diploma / GED and 8 years of Engineering experience
Preferred Qualifications:
- BS or MS in Chemical Engineering
- Alternatively, life science or related field with 5 years relevant experience
- Previous industrial hands-on experience in a GMP chemical manufacturing environment
- Strong familiarity with safe chemical handling techniques including weighing, dispensing, and packaging of chemicals, drug substance intermediates, and APIs
- In depth understanding of typical unit operations for the manufacture of synthetics drug product (i.e. granulation, roller compaction, drying, milling, blending, compression, encapsulation and film coating)
- Ability to perform preventive maintenance and troubleshooting on manufacturing equipment.
- PPE familiarity and ability to use a chemical respirator
- Experience with laboratory automation including temperature control and data logging platforms such as Delta V
- Excellent verbal and written communication skills
- Proficiency with Microsoft Word, Excel, and PowerPoint
- Advanced scientific/technical reading/writing skills, advanced scientific analysis skills, ability to collaborate and work in team environment
- Strong familiarity with Good Documentation Practices
- Strong interpersonal skills and a proactive leadership mindset
- Ability to work independently and as part of a team, self-motivation, adaptability, and a positive attitude
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
careers.amgen.com
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.