Director, Web Platform Engineering

Key Responsibilities

Web Platform Strategy & Architecture

• Conduct a comprehensive currentstate assessment of Alnylam's global web technology stack (CMS, hosting, analytics, consent management, DAM, personalization, integrations, and related tools).
• Define and maintain a futurestate web platform strategy aligned to global scale, localization needs, performance expectations, and compliance requirements.
• Establish reference architectures, standards, and technical frameworks for corporate and brand sites across regions.
• Ensure alignment and interoperability with Alnylam enterprise platforms including CRM, CDP, Marketing Automation, Identity, and Analytics tools.

Global Scale & Operating Model

• Design and operationalize, in partnership with Customer Experience & Innovation, a scalable global operating model for web technology- balancing central governance with regional agility.
• Define roles, responsibilities, and working models across relevant cross-functional teams and agency partners.
• Develop standardized processes and reusable patterns for new site launches, upgrades, migrations, localization, and ongoing website operations.

Governance, Compliance & Risk Management

• Ensure all web platforms adhere to regulatory, privacy, and security standards (e.g., GxP, GDPR, HIPAA, cookie/consent frameworks).
• Lead governance for web change management, release planning, validation approaches, documentation standards, and operational controls.
• Conduct technology risk assessments and guide remediation activities across the ecosystem.

Delivery & Operations

• Oversee enterprise web platform operations, including uptime, availability, site performance, incident response, and SLA adherence.
• Build and manage KPIs for platform health, delivery velocity, quality, cost efficiency, and business value realization.
• Lead modernization initiatives including CMS/platform upgrades, architectural transitions, and remediation of legacy systems.

Vendor & Partner Management

• Manage relationships with CMS providers, hosting platforms, system integrators, and digital agencies.
• Oversee RFPs, vendor selection, contract negotiations, and performance management.
• Ensure thirdparty partners follow architectural principles, security requirements, and Alnylam's delivery expectations.

Leadership & Stakeholder Engagement

• Serve as a trusted advisor to senior leaders across Technology, Commercial, Corporate Communications, and regional teams.
• Communicate complex technical concepts in a clear, accessible manner tailored to nontechnical audiences.
• Provide leadership to matrixed teams supporting web platforms.

Qualifications

Required

• 10 years of experience in web technology, digital platforms, or enterprise digital solutions, with increasing leadership responsibility.
• Demonstrated success leading global web platforms within regulated industries (pharma/biotech, healthcare, medical devices, or similarly regulated).
• Deep expertise with modern CMS platforms (e.g., Acquia/Drupal, Sitecore, AEM).
• Experience with:
  • Cloud hosting (AWS, Azure), CDN, security, and web infrastructure
  • Web analytics, tag management, and performance measurement
  • Consent/privacy management tools
  • DAM integrations and content workflows
• Strong understanding of GxP, validation methodologies, security frameworks, and privacy regulations for web ecosystems.
• Proven ability to define current state, architect future state, and execute transformation roadmaps.

Preferred

• Experience scaling web platforms in a midsize or highgrowth organization.
• Familiarity with headless, composable, or APIdriven architectures.
• Handson experience integrating web platforms with CRM, CDP, marketing automation, and personalization systems.
• Background in agile or productoriented delivery models.
• Bachelor's degree required; advanced degree preferred.

Key Competencies

• Strategic thinking & enterprise architecture leadership
• Global operating model design & execution
• Regulatory, compliance, and risk management fluency
• Vendor, budget, and performance management
• Executiveready communication and influence
• Pragmatic, handson problem solving and ability to roll up your sleeves
• Ability to operate in a fastpaced, growing, patientfocused organization
• Location: Cambridge, MA (Hybrid role; 3 days/week onsite)

#LI-Hybrid

#LI-LN1

U.S. Pay Range

$187,400.00 - $253,600.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

AboutAlnylam

We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.