Manager, Commercial Supply Chain

Who we are:

At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X .

The impact you will make:

Agios Pharmaceuticals is searching for a dynamic Manager, Commercial Supply Chain to join our growing team. Agios outsources all cGMP manufacturing operations to third party CMOs across API, bulk drug product, and final packaged goods. The selected individual will have full exposure across the different areas of the commercial supply chain and across early clinical to new commercial product launches. The individual will also support our growing global footprint as our distribution expands to other markets outside of the US which will also have responsibilities for life cycle management. Additionally, this role will be responsible for supporting the commercial supply chain department across systems, planning and operations

What you will do:

Key Responsibilities

• As a member of cross functional teams that include CMC, QA, and Regulatory; execute activities for Commercial Supply Chain Operations team on assigned projects.
• Oversee timelines for both internal activities and external production activities at Contract Manufacturing Organizations (CMOs) to ensure continuous supply of Commercial and Clinical materials through the supply chain.
• Responsible for accurate inventory in Agios’ inventory management system including production, data entry and reporting.
• Support commercial artwork changes for existing commercial products and collaborate with artwork team to develop new artwork for new product or market launches.
• Ownership of change controls and support for deviation investigations and other quality events.
• Collaborate with Finance and Cost accounting team to ensure proper inventory accounting financial reporting.
• Issue POs and track invoices to ensure project budget is maintained.
• Maintain and communicate production schedule at all inventory levels.
• Oversee and maintain production KPIs for each supplier.
• Project management department projects including product launch activities to ensure that action items are identified and tracked against a project plan.
• Support supply planning for both clinical supply chain and commercial supply chain (as needed)
  
  

What you bring:

Minimum Requirements

• BS degree in Engineering, Business, Supply Chain/Material Management or life science field.
• 5 year experience in supply chain or GMP manufacturing environment.
• Experience using ERP/SAP
• Ability to Travel 25% for production or supplier oversight.
• Must be detail focused with an ability to influence suppliers and projects with minimal oversight yet work collaboratively in a team environment.
  
  

Preferred Qualifications

• Experience working with CMO partners
• Experience with new product launches
• Experience with continuous manufacturing
• Experience with EU/GCC regional requirements
  
  

Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening!

Work Location:

Location Agnostic: Work location for this role is based on employee's individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above job description..

What we will give you:

• Deliberate Development. Your professional growth as one of our top priorities.
• Flexibility.We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best.
• Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website.
• Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance.
• The current base salary range for this position is expected to be between $110,029 and $165,044 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators.
• Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries.
• Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce.
• Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.
  
  

Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.