Demo

Medical Director - I&I Clinical Development

Aerial Talent
South San Francisco, CA Full Time
POSTED ON 5/12/2026
AVAILABLE BEFORE 6/10/2026

An emerging, pre-IPO biotech in South San Francisco focused on advancing a first-in-class therapeutic platform with the potential to unlock previously intractable targets is growing their clinical development team. As multiple programs move into the clinic, the team is seeking a Medical Director to help lead FIH and early-phase studies. Experience in inflammatory or autoimmune diseases preferred.


This is a high-impact role for a physician who wants to shape early clinical strategy and operational execution, work closely with cross-functional teams, and help bring novel therapies into the clinic.


South San Francisco, CA - Hybrid Remote Flexibility


Why This Role


  • First-in-class science with a novel approach to protein degradation
  • Multiple programs approaching FIH
  • Opportunity to own meaningful pieces of early clinical development
  • Backed by strong funding with a deep, innovative pipeline


What You’ll Do


  • Help drive first-in-human and early-phase clinical trials from startup through readout
  • Provide clinical insight and safety perspective on emerging data
  • Partner closely with CROs and internal teams to ensure high-quality study execution
  • Contribute to dose-escalation decisions, data interpretation, and key clinical deliverables
  • Engage with investigators and support study-level strategy and execution
  • Additional responsibilities as needed


What We’re Looking For


  • MD with biotech/pharma experience
  • Background in early-phase clinical development (Phase 1 or 2)
  • Interest in novel mechanisms and innovative science
  • Collaborative, hands-on, and motivated by impact in a small-team environment
  • Background in inflammatory, autoimmune, allergy, or endocrine-related diseases a plus

Salary : $225,000 - $325,000

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