Scientist

USA-Scientist III (Scientific)

Location: Cambridge, MA - onsite

Duration: Contract till Sep 2026 with possibility to extend

Shift: 1st, Monday to Friday

Note:

Required:

PhD in Immunology, Neuroscience, Cell Biology, or a related field with 1–3 years of postdoctoral or industry experience OR Bachelor's or Master's degree in a relevant scientific discipline with 4–7 years of hands-on laboratory research experience

• Experience in neuroimmunology, including knowledge of immune cell biology in neurological or ophthalmic diseases
• Expertise in assay development and troubleshooting, with the ability to independently design, optimize, and validate experimental protocols
• Proficiency in ELISA/MSD for quantitative protein detection and multiplex analysis
• Experience with cell culture, including maintenance and passaging of adherent cell lines as well as iPSC-derived cell types
• Experience working with primary immune cells (e.g., isolation, activation, and functional characterization)

Preferred Qualifications:

· Experience with co-culture systems or advanced in vitro models (e.g., organoids, 3D cultures, organ-on-a-chip)

· Experience with live-cell and high-content imaging and analyses

· Background or research experience in retinal disease

Job Description:

Description:

We are seeking a motivated and skilled Scientist to join our Retinal Immunology and Neuroinflammation team as a contingent worker. The successful candidate will contribute to cutting-edge research aimed at understanding immune mechanisms in retinal diseases, supporting our mission to develop transformative therapies for patients.

Education & Experience Requirements

PhD in Immunology, Neuroscience, Cell Biology, or a related field with 0–3 years of postdoctoral or industry experience OR Bachelor's or Master's degree in a relevant scientific discipline with 4–7 years of hands-on laboratory research experience

Required Qualifications:

· Demonstrated experience in neuroimmunology, including knowledge of immune cell biology in neurological or ophthalmic diseases

· Proven expertise in assay development and troubleshooting, with the ability to independently design, optimize, and validate experimental protocols

· Proficiency in ELISA/MSD for quantitative protein detection and multiplex analysis

· Experience with cell culture, including maintenance and passaging of adherent cell lines as well as iPSC-derived cell types

· Experience working with primary immune cells (e.g., isolation, activation, and functional characterization)

· Ability to work independently in a laboratory setting, managing experiments with minimal supervision while maintaining rigorous scientific standards

· Strong cross-functional collaboration skills, with the ability to work effectively across teams

Preferred Qualifications:

· Experience with co-culture systems or advanced in vitro models (e.g., organoids, 3D cultures, organ-on-a-chip)

· Experience with live-cell and high-content imaging and analyses

· Background or research experience in retinal disease

Main Responsibilities

· Design and execute experiments to investigate and translate immune and neuroinflammatory mechanisms into therapeutic disease programs, supporting target validation from discovery through preclinical development

· Collaborate cross-functionally with internal teams and external partners to support the screening of preclinical candidates across diverse modalities, using target- and disease-relevant functional readouts to drive program decisions

· Develop, optimize, and validate immunological and cell-based assays in support of research programs

· Maintain accurate and detailed laboratory records in compliance with internal documentation standards

· Analyze, interpret, and present experimental data to internal stakeholders

· Contribute to scientific discussions and help drive innovation within the team

Competencies

· Strong analytical and problem-solving skills

· Excellent written and verbal communication

· Detail-oriented with a commitment to data integrity and reproducibility

· Adaptable and proactive in a fast-paced research environment

· Collaborative mindset with a patient-focused approach to science