Senior Scientist

Position Summary

We are partnering with an innovative gene therapy organization in the RTP area seeking a Senior Scientist to support bioanalytical and molecular biology research activities. This individual will play a key role in executing and optimizing a variety of molecular and cellular assays focused on DNA, RNA, proteins, and cell-based systems. The ideal candidate brings strong technical expertise, experience in fast-paced biotech environments, and a collaborative, solution-oriented mindset.

Key Responsibilities

• Execute molecular biology experiments involving nucleic acids, proteins, and mammalian or bacterial cell systems.
• Perform and troubleshoot techniques including PCR, qPCR, ddPCR, cloning, sequencing, plasmid preparation, CE, ELISA, SDS-PAGE, and Western blotting.
• Design, clone, evaluate, and optimize AAV GOI plasmid constructs.
• Develop, refine, and document laboratory assays, workflows, and experimental procedures.
• Maintain laboratory inventory, reagents, and instrumentation to support efficient lab operations.
• Review current scientific literature and incorporate emerging molecular biology methodologies as appropriate.
• Support additional laboratory and research activities as needed.

Qualifications

• Bachelor’s, Master’s, or PhD degree in Life Sciences or a related scientific discipline.
• Minimum of 2 years of relevant hands-on molecular biology experience in a laboratory setting.
• Strong expertise in recombinant DNA cloning, plasmid isolation, and molecular analysis techniques.
• Experience with large-scale plasmid DNA preparation and ITR-containing plasmids.
• Proficiency with analytical and molecular techniques including PCR, qPCR, ddPCR, CE, ELISA, SDS-PAGE, and Western blotting.
• Experience developing SOPs, laboratory protocols, and analytical procedures.
• Working knowledge of GLP, GCLP, or related quality standards.
• Strong communication, organizational, and collaboration skills.
• Demonstrated ability to work independently while contributing effectively within a team environment.
• Proficiency with Microsoft Office Suite, SoftMax, JMP, and GraphPad Prism.

Equal Employment Opportunity

We are committed to fostering a diverse and inclusive workplace. All qualified applicants will receive consideration for employment without regard to any protected status under applicable law.