Demo

Associate Scientist, Medicinal Chemistry

Actalent
Redwood City, CA Full Time
POSTED ON 1/14/2023 CLOSED ON 2/9/2023

What are the responsibilities and job description for the Associate Scientist, Medicinal Chemistry position at Actalent?

Description:

Clinical-stage precision oncology company focused on developing novel targeted therapies to

inhibit high-value frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors

designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination

treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a

tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

As a key member of the Medicinal Chemistry team, you will be part of an integrated, multidisciplinary research team

making significant contributions toward the discovery of important new drug candidates. Your responsibilities will

include:

• Synthesizing biologically active compounds, including the design and execution of the synthetic routes,

purification of final targets, and participating in analog design.

• Plan and execute assigned experiments to support research activities and project goals.

• Recommend alternatives, research new methods and techniques through literature search and proactively seek

out others to identify solutions to challenges.

• Present research findings to the Medicinal Chemistry team and management.

• Partner in the scientific activities of other outstanding medicinal chemists, including Ph.D. scientists, and create

an environment where all ideas are heard.

• Uphold the core values at Revolution Medicines: i) tireless commitment to patients ii) transformative science

iii) exceptional together iv) total integrity and v) inclusiveness and fairness.

Skills:

Chemistry, medicinal chemistry, synthesis, HPLC, NMR, nmr spectroscopy, natural product synthesis, discovery chemistry, mass spectrometry

Top Skills Details:

Chemistry,medicinal chemistry,synthesis,HPLC,NMR,nmr spectroscopy,natural product synthesis,discovery chemistry

Additional Skills & Qualifications:

Required Experience, Skills, and Education:

• B.S. degree in Chemistry with 1 years of research experience in, or an M.S. in Chemistry with a focus on organic

synthesis and/or methodology development.

• Strong mechanistic understanding of organic chemistry is highly preferred.

• Experience with chemistry search engines (i.e. SciFinder and Reaxyx) to design and plan synthetic routes is

preferred but not a must.

• High attention to details, especially in NMR, HPLC, mass spectrometry techniques, is preferred.

• Experience with synthetic methodologies to design, execute synthetic procedures, and troubleshoot reactions

• Strong written and verbal communication skills to work with interdepartmental teams.

• Ability to multi-task, be efficient and well-organized, and work collaboratively as a team player with passion for

science.

• Adaptive to a fast-paced interdisciplinary environment with a strong desire to further develop synthetic and

medicinal chemistry skills.

Experience Level:

Entry Level

About Actalent:

Actalent connects passion with purpose. Our scalable talent solutions and services capabilities drive value and results and provide the expertise to help our customers achieve more. Every day, our experts around the globe are making an impact. We’re supporting critical initiatives in engineering and sciences that advance how companies serve the world. Actalent promotes consultant care and engagement through experiences that enable continuous development. Our people are the difference. Actalent is an operating company of Allegis Group, the global leader in talent solutions.

The company is an equal opportunity employer and will consider all applications without regards to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

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