What are the responsibilities and job description for the Research Associate / Senior Research Associate position at 5AM Ventures?
Company OverviewWe’re looking for teammates who relish the challenge and are compelled to leave a positive mark on the lives of the patients we serve. If embracing creativity and candor, thriving on challenges, and empowering your teammates to succeed excites you, join us as we champion hope and advance therapies for cystic kidney disease. The RoleWe’re seeking a highly motivated research associate with a strong background in cell cultureto join our dynamic team and contribute to building our pipeline for kidney diseases. The successfulcandidate will play a crucial role in supporting our research efforts working alongside a team of scientists. Responsibilities include maintaining and propagating cell lines, executing experiments, and ensuring the quality and consistency of our cell culture processes. The ideal candidate should have at least 3-5 years of hands-on experience in mammalian cell culture techniques and possess a strong understanding of laboratory safety protocols.Major ResponsibilitiesInitiate and maintain cystogenesis assays by culturing kidney epithelial cells in 3D-extracellular matrices. Routinely apply defined media supplements to stimulate cyst formationPerform compound treatment studies within cystogenesis assays. Prepare dosing solutions, apply treatments and document observations.Establish and characterize new stable cell linesSupport all other cell culture and cell-based assay activities, including high-throughput assay workflows and routine maintenance, expansion, and cryopreservation of mammalian cell linesPrepare media, supplements, and other cell culture reagents in support of cell culture needsMaintain accurate and detailed records of experiments, protocols, and resultsAdhere to strict laboratory safety guidelines and ensure a clean and organized work environmentCollaborate within the Discovery Biology team to optimize assay conditions, interpret outcomes, and ensure consistent assay reproducibilityCommit to helping the team achieve deliverables and meet aggressive timelinesRequirements and QualificationsBachelor's degree in a relevant scientific field with 3-5 years of hands-on experience in mammalian cell culture techniques. Prior work industry experience is required.Demonstrated proficiency with sterile technique and independent handling of multiple mammalian cell linesExperience with cell-based assays, viability assays, and stable cell line generationKnow-how of 3D in vitro models is advantageousExperience with fundamental molecular biology techniques, including DNA/RNA and protein isolation, quantitative PCR, and protein analysis is desirable.Strong attention to detail with excellent organizational and time management skills.Effective communication and interpersonal skills, with the ability to work collaboratively in a team environment.Commitment to maintaining high-quality standards and adhering to laboratory safety protocols.Final compensation will be based on a candidate’s qualifications, experience, and geographic location. Employees are also eligible for performance bonuses, equity participation and comprehensive health benefits.We believe in building balanced teams. We are an equal opportunity employer. We do not discriminate in regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, marital status, ancestry, physical or mental disability, veteran status, or any other legally protected characteristics.We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
Salary : $33 - $36