US Senior Medical Director – Early Assets, Immunology

Are you ready to turn ideas into life-changing medicines? At AstraZeneca, we are committed to addressing the unmet needs of patients worldwide through scientific innovation. As a Senior Medical Director, Immunology Early Assets, you will play a crucial role in leveraging our scientific capabilities to positively impact patients' lives. Reporting directly to the US Medical Head, Immunology, you will lead the development of ambitious US medical strategies for our early pipeline of immunology products, including cell therapies. This is an opportunity to seize, design, and influence across a complex matrix system to ensure US needs are integrated into global development plans. Accountabilities: As a strategic leader, you will shape the scientific and medical direction for novel therapies (e.g. cell therapies), ensuring alignment with pipeline priorities and business objectives - while supporting efforts on lifecycle management of current in-line assets. You will serve as the internal medical expert for emerging assets, collaborating cross-functionally with global teams and external partners. You will partner with global medical and R&D to ensure robust translational and early clinical development plans, incorporating medical insights and real-world data opportunities. Your role will involve crafting compelling scientific narratives, developing solutions for outstanding product launches, and optimizing evidence activities to support practice change initiatives. You will also ensure comprehensive external engagement plans and play an integral role in medical advisory boards. Essential Skills/Experience: Doctoral level degree: MD, PhD, or PharmD 5 years of experience in the pharmaceutical industry (medical, marketing, R&D, market access roles), or working in a relevant health system setting (clinical, pharmacy, pathway design etc.) Deep medical, clinical or scientific expertise in immunology and/or cell therapy Experienced business leader able to deliver results in a complex matrix environment US regulatory strategy knowledge including product approval, label requirements/negotiation Proven ability to build internal/external networks and to collaborate internally/externally Substantial evidence generation/data expertise, e.g. clinical trial experience (conducted Ph2, Ph3 or Ph4 studies), and/or substantial RWE experience Desirable Skills/Experience: Global and/or R&D experience, or proven track record of supporting early asset or first-in-class product development Relevant experience beyond medical affairs (e.g. in a marketing/R&D/market access role) When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. AstraZeneca offers an environment where you can thrive on energy and pace while making a significant impact on patients' lives. Our commitment to innovation and experimentation empowers our teams to think big and act fast. With countless opportunities for growth and development, you'll be part of a journey that shapes the future of BioPharmaceuticals and contributes to bending the global mortality curve. Ready to make a difference? Apply now and join us on this exciting journey! Date Posted 06-Nov-2025 Closing Date 26-Nov-2025 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.